Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ACLV65_RS08565 Genome accession   NZ_OZ217342
Coordinates   1724136..1724825 (-) Length   229 a.a.
NCBI ID   WP_000518030.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis B22     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1719136..1729825
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV65_RS08545 (SMIB22_16830) mvaD 1719658..1720611 (-) 954 WP_261091126.1 diphosphomevalonate decarboxylase -
  ACLV65_RS08550 (SMIB22_16840) mvk 1720593..1721471 (-) 879 WP_411865052.1 mevalonate kinase -
  ACLV65_RS08555 (SMIB22_16850) cbpC 1721594..1722673 (-) 1080 WP_411865053.1 choline-binding protein CbpC -
  ACLV65_RS08560 (SMIB22_16860) - 1722691..1724025 (-) 1335 WP_411865054.1 trypsin-like peptidase domain-containing protein -
  ACLV65_RS08565 (SMIB22_16870) covR 1724136..1724825 (-) 690 WP_000518030.1 response regulator transcription factor Regulator
  ACLV65_RS08570 (SMIB22_16880) gndA 1724837..1726261 (-) 1425 WP_000158778.1 NADP-dependent phosphogluconate dehydrogenase -
  ACLV65_RS08575 (SMIB22_16890) mapZ 1726337..1727743 (-) 1407 WP_411865055.1 cell division site-positioning protein MapZ -
  ACLV65_RS08580 (SMIB22_16900) - 1727756..1728913 (-) 1158 WP_411865056.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  ACLV65_RS08590 (SMIB22_16930) gpsB 1729399..1729740 (-) 342 WP_000146532.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26766.86 Da        Isoelectric Point: 7.4648

>NTDB_id=1170141 ACLV65_RS08565 WP_000518030.1 1724136..1724825(-) (covR) [Streptococcus mitis isolate S. mitis B22]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNAHLGDMTAQDFADKLSRTKPASVIMVL
DHREELQDQLETIQRFAVSYIYKPVIIDNLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1170141 ACLV65_RS08565 WP_000518030.1 1724136..1724825(-) (covR) [Streptococcus mitis isolate S. mitis B22]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCACTTTTTAAGTTTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTTGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGACTTGATTTTATTGAATG
CTCATCTGGGGGATATGACAGCCCAGGATTTTGCAGATAAGCTGAGTCGAACTAAGCCAGCTTCAGTCATCATGGTCTTG
GACCATCGTGAAGAATTGCAAGACCAGCTTGAGACAATCCAACGCTTTGCCGTTTCTTATATCTATAAGCCAGTAATTAT
TGATAATTTGGTAGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTCATCGACCAACACTGTAGTCAGATGAAGGTTC
CAACGTCTTACCGCAATCTGCGTATGGATGTAGAGCATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACCCGT
CGTGAGTATGACCTTCTGGCTACTCTCATGGGAAGCAAGAAGGTTCTGACTCGTGAGCAGTTATTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAGACCAATATCGTGGATGTCTATATTCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTAGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.491

99.563

0.463

Multiple sequence alignment