Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   ACLV65_RS06100 Genome accession   NZ_OZ217342
Coordinates   1199543..1201345 (-) Length   600 a.a.
NCBI ID   WP_218773966.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis B22     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1194543..1206345
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV65_RS06065 (SMIB22_11910) - 1195027..1195869 (+) 843 WP_411864791.1 DUF368 domain-containing protein -
  ACLV65_RS06070 (SMIB22_11920) - 1195869..1196351 (+) 483 WP_411864792.1 aminoacyl-tRNA deacylase -
  ACLV65_RS06075 (SMIB22_11930) - 1196351..1196971 (+) 621 WP_411864793.1 histidine phosphatase family protein -
  ACLV65_RS06080 - 1197250..1197408 (-) 159 WP_237701464.1 hypothetical protein -
  ACLV65_RS06085 - 1197420..1197515 (-) 96 Protein_1152 IS630 family transposase -
  ACLV65_RS06090 (SMIB22_11940) prsA 1197823..1198761 (-) 939 WP_218773968.1 peptidylprolyl isomerase PrsA -
  ACLV65_RS06095 (SMIB22_11950) - 1198828..1199541 (-) 714 WP_218773967.1 O-methyltransferase -
  ACLV65_RS06100 (SMIB22_11960) pepF 1199543..1201345 (-) 1803 WP_218773966.1 oligoendopeptidase F Regulator
  ACLV65_RS06105 (SMIB22_11970) coiA 1201364..1202317 (-) 954 WP_218773965.1 competence protein CoiA Machinery gene
  ACLV65_RS06110 (SMIB22_11980) - 1202396..1202773 (-) 378 WP_050252888.1 type II toxin-antitoxin system HicB family antitoxin -
  ACLV65_RS06115 (SMIB22_11990) - 1202801..1202989 (-) 189 WP_001122912.1 type II toxin-antitoxin system HicA family toxin -
  ACLV65_RS06120 (SMIB22_12000) tehB 1203111..1203971 (-) 861 WP_411864794.1 SAM-dependent methyltransferase TehB -
  ACLV65_RS06125 (SMIB22_12010) smpB 1203987..1204454 (-) 468 WP_001051750.1 SsrA-binding protein SmpB -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69898.74 Da        Isoelectric Point: 4.5061

>NTDB_id=1170127 ACLV65_RS06100 WP_218773966.1 1199543..1201345(-) (pepF) [Streptococcus mitis isolate S. mitis B22]
MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYEGHLLDSADSLLEITEFSLEMERQMEKLYVYAHMKND
QDTREAKYQEYYAKAMTLYSQIDQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKNREVRRGAYQALYATYEQFQHTYAKTLQTNVKVQ
NYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALK
KAEDALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYTRET
QPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDETRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSDF
LNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPL
NVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=1170127 ACLV65_RS06100 WP_218773966.1 1199543..1201345(-) (pepF) [Streptococcus mitis isolate S. mitis B22]
ATGGTATTACAAAGAAATGAAATAAATGAAAAAGATACATGGGATCTATCAACGATCTACCCAACTGACCAGGCTTGGGA
AGAAGCCTTAAAAGATTTAACAGAACAATTGGAGACAGTAGCCCAGTATGAAGGCCATCTCCTGGATAGTGCGGATAGCC
TACTCGAAATTACTGAATTTTCTCTTGAAATGGAACGCCAAATGGAGAAGCTTTACGTTTATGCTCATATGAAAAATGAC
CAGGACACACGTGAAGCCAAGTACCAAGAGTACTATGCCAAGGCCATGACACTCTATAGCCAGATAGACCAAGCCTTTTC
ATTCTATGAACCTGAATTTATGGAAATTAGTGAAAAGCAGTATGCTGACTTTTTAGAAGCTCAGCCAAAATTGCAGGTTT
ATCAACACTATTTTGACAAGCTTTTGCAAGGCAAGGATCACGTTCTTTCACAACGCGAGGAAGAATTATTGGCTGGCGCT
GGAGAAATCTTTGGTTCGGCCAGTGAAACCTTCGCTATCTTGGACAATGCGGATATTGTTTTCCCTTATGTTCTTGACGA
TGATGGTAAGGAAGTGCAGCTCTCTCATGGGACTTACACACGTTTGATGGAGTCTAAAAATCGTGAGGTTCGCCGTGGTG
CCTATCAAGCCCTTTATGCGACTTATGAACAATTCCAACACACCTATGCCAAAACCTTGCAAACCAATGTTAAGGTTCAA
AACTATCGTGCAAAAGTTCGCAACTACAAGAGCGCTCGTCATGCGGCTCTAGCAGCCAATTTTGTTCCAGAGAGTGTTTA
TGACAATTTGGTAGCAGCAGTTCGCAAGCATTTGCCACTCTTGCATCGTTACCTTGAGCTTCGTTCAAAAATCTTGGGAA
TTTCAGACCTTAAGATGTACGATGTCTACACACCGCTTTCATCTGTTGAATACAGTTTTACCTACCAAGAAGCCTTGAAA
AAGGCAGAAGATGCCTTGGCAGTCTTGGGTGAGGATTACTTGAGCCGTGTTAAACGTGCCTTCAGTGAGCGTTGGATTGA
TGTTTACGAAAATCAAGGCAAGCGTTCAGGTGCCTACTCTGGTGGTTCTTACGATACCAATGCCTTTATGCTTCTCAACT
GGCAGGACAATCTGGACAATCTCTTTACTCTTGTTCATGAAACAGGTCACAGTATGCATTCAAGCTATACTCGTGAAACG
CAACCTTATGTTTACGGAGATTATTCTATCTTCTTGGCTGAGATTGCATCAACTACCAATGAAAATATCTTGACGGAGAA
ATTATTGGAAGAAGTGGAAGACGACGAAACGCGCTTTGCTATTCTCAATAACTTCCTAGATGGTTTCCGTGGAACAGTTT
TCCGCCAAACTCAATTTGCTGAGTTTGAACACGCTATCCATCAAGCAGACCAAAATGGGGAAGTTTTGACAAGCGATTTC
TTAAATAAACTCTACGCAGACTTGAACCAAGAGTATTATGGTTTGAGTAAGGAAGACAATCCTGAAATCCAATACGAGTG
GGCTCGGATTCCACACTTCTACTATAACTACTATGTATATCAATATTCAACAGGCTTTGCGGCGGCCTCAGCCTTGGCTG
AAAAGATTGTCCATGGTAGTCAAGAAGACCGTGACCGCTATATCGACTATCTCAAGGCAGGTAAGTCTGACTATCCACTT
AATGTCATGAGAAAAGCTGGTGTTGATATGGAGAAGGAAGACTACCTCAACGATGCCTTTGCAGTCTTTGAACGCCGTTT
AAATGAGTTTGAAGCCCTTGTTGAAAAATTGGGATTGGCATAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(112-181)

Peptidase family M3 (Peptidase_M3)

(202-581)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.114

99.333

0.667

Multiple sequence alignment