Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ACLV7Q_RS08660 Genome accession   NZ_OZ217341
Coordinates   1788647..1789336 (-) Length   229 a.a.
NCBI ID   WP_000518028.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis C22     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1783647..1794336
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Q_RS08635 (SMIC22_17000) fni 1783705..1784715 (-) 1011 WP_218757187.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  ACLV7Q_RS08640 (SMIC22_17010) - 1784699..1785706 (-) 1008 WP_218757188.1 phosphomevalonate kinase -
  ACLV7Q_RS08645 (SMIC22_17020) mvaD 1785693..1786646 (-) 954 WP_218757189.1 diphosphomevalonate decarboxylase -
  ACLV7Q_RS08650 (SMIC22_17030) mvk 1786628..1787506 (-) 879 WP_218757190.1 mevalonate kinase -
  ACLV7Q_RS08655 (SMIC22_17040) - 1787630..1788547 (-) 918 WP_218757191.1 N-acetylmuramoyl-L-alanine amidase family protein -
  ACLV7Q_RS08660 (SMIC22_17050) covR 1788647..1789336 (-) 690 WP_000518028.1 response regulator transcription factor Regulator
  ACLV7Q_RS08665 (SMIC22_17060) gndA 1789348..1790772 (-) 1425 WP_000158778.1 NADP-dependent phosphogluconate dehydrogenase -
  ACLV7Q_RS08670 (SMIC22_17070) mapZ 1790848..1792254 (-) 1407 WP_218757192.1 cell division site-positioning protein MapZ -
  ACLV7Q_RS08675 (SMIC22_17080) - 1792267..1793424 (-) 1158 WP_218757193.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  ACLV7Q_RS08685 (SMIC22_17110) gpsB 1793910..1794251 (-) 342 WP_000146532.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26780.89 Da        Isoelectric Point: 7.4648

>NTDB_id=1170059 ACLV7Q_RS08660 WP_000518028.1 1788647..1789336(-) (covR) [Streptococcus mitis isolate S. mitis C22]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNAHLGDMTAQDFADKLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIENLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1170059 ACLV7Q_RS08660 WP_000518028.1 1788647..1789336(-) (covR) [Streptococcus mitis isolate S. mitis C22]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTTGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGACTTGATTTTATTGAATG
CTCATCTGGGGGATATGACAGCCCAGGATTTTGCAGATAAGCTGAGTCGGACTAAGCCAGCTTCAGTCATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGATCAGATTGAGACAATCCAACGCTTTGCCGTTTCTTACATCTATAAGCCAGTTATTAT
TGAGAATCTGGTAGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTCATCGACCAACACTGTAGTCAGATGAAGGTTC
CAACATCTTACCGCAATCTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAAGAGATGATTGCTCTGACGCGT
CGTGAGTATGACCTTCTGGCTACTCTCATGGGAAGCAAGAAAGTTCTGACTCGTGAGCAGTTGTTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAGACTAATATCGTGGATGTCTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACAGTACGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467

Multiple sequence alignment