Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   ACLV7H_RS01510 Genome accession   NZ_OZ217340
Coordinates   265678..266502 (+) Length   274 a.a.
NCBI ID   WP_045593588.1    Uniprot ID   A0A0F2CV79
Organism   Streptococcus oralis isolate S. oralis A22     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 260678..271502
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7H_RS01475 (SORA22_02870) rsmD 260733..261272 (+) 540 WP_411866169.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  ACLV7H_RS01480 (SORA22_02880) coaD 261262..261750 (+) 489 WP_411866170.1 pantetheine-phosphate adenylyltransferase -
  ACLV7H_RS01485 (SORA22_02890) sepM 261734..262771 (+) 1038 WP_049501597.1 SepM family pheromone-processing serine protease Regulator
  ACLV7H_RS01490 - 262827..263057 (+) 231 WP_411866171.1 DUF1146 family protein -
  ACLV7H_RS01495 (SORA22_02900) - 263118..264161 (+) 1044 WP_411866172.1 acyltransferase family protein -
  ACLV7H_RS01500 (SORA22_02910) murA 264173..265456 (+) 1284 WP_411866173.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  ACLV7H_RS01505 (SORA22_02920) - 265443..265637 (+) 195 WP_000739701.1 DNA-directed RNA polymerase subunit beta -
  ACLV7H_RS01510 (SORA22_02930) endA 265678..266502 (+) 825 WP_045593588.1 DNA/RNA non-specific endonuclease Machinery gene
  ACLV7H_RS01515 (SORA22_02940) - 266638..267969 (+) 1332 WP_411866174.1 hemolysin family protein -
  ACLV7H_RS01525 (SORA22_02960) amiA3 268476..270455 (+) 1980 WP_411866175.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29957.58 Da        Isoelectric Point: 9.7190

>NTDB_id=1169938 ACLV7H_RS01510 WP_045593588.1 265678..266502(+) (endA) [Streptococcus oralis isolate S. oralis A22]
MDKKTRQALIGLLIFLLLSAGSYYIKQMQSAPNTPRTKVSQKKQTSEAPSQELAESVLTESIKNQIKGGLEWNGAGAFII
NGNKTNLDAKVSSKPYADNKTKPVGKETVPTVANAILSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGAYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESLVRKALDQNKRVRYRVTLHYATNEDLVPSASQIE
AKSSDGELEFNVLIPNVQKGIQLDYQTGQVTVTD

Nucleotide


Download         Length: 825 bp        

>NTDB_id=1169938 ACLV7H_RS01510 WP_045593588.1 265678..266502(+) (endA) [Streptococcus oralis isolate S. oralis A22]
ATGGACAAGAAAACAAGACAGGCTCTGATAGGGTTACTCATATTCTTACTATTATCTGCTGGTAGTTATTACATCAAGCA
GATGCAGTCAGCGCCAAACACCCCTAGAACAAAGGTTAGTCAGAAAAAACAAACTTCAGAAGCTCCCAGTCAAGAGTTGG
CAGAAAGTGTCTTAACTGAGTCAATCAAAAATCAAATCAAGGGGGGGCTCGAGTGGAATGGGGCAGGTGCCTTCATTATC
AATGGCAATAAAACCAATCTAGATGCCAAAGTTTCTAGCAAACCCTATGCGGATAATAAAACAAAACCAGTTGGAAAAGA
AACAGTTCCAACTGTTGCCAATGCCATCTTATCCAAAGCGACTCGGCAGTATAAGAATCGTGAAGAAACAGGCAATGGCT
CAACCTCTTGGACGCCACCAGGATGGCATCAGGTTAAGAATCTAAAGGGAGCCTACACACATGCAGTTGATAGAGGACAC
CTGCTGGGCTATGCCTTGATAGGTGGTTTGGATGGTTTTGATGCCTCTACCAGCAATCCCAAGAACATTGCAGTCCAGAC
AGCTTGGGCGAACCAGGCTCAGGCTGAGGATTCGACAGGTCAGAACTACTATGAGAGTTTGGTCAGAAAAGCCTTGGACC
AAAATAAGAGGGTCCGTTATCGCGTGACGCTCCACTATGCGACTAATGAGGACCTAGTTCCATCCGCTTCACAAATCGAA
GCCAAGTCTTCAGATGGCGAATTGGAATTCAATGTCCTAATCCCCAATGTTCAAAAGGGAATCCAGCTTGATTACCAAAC
GGGTCAAGTAACAGTGACGGACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F2CV79

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

88.645

99.635

0.883
  endA Streptococcus pneumoniae D39

88.645

99.635

0.883
  endA Streptococcus pneumoniae R6

88.645

99.635

0.883
  endA Streptococcus pneumoniae TIGR4

88.645

99.635

0.883

Multiple sequence alignment