Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   ACNUDV_RS12465 Genome accession   NZ_OZ197092
Coordinates   2527271..2527840 (+) Length   189 a.a.
NCBI ID   WP_000872866.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 23S00050-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2522271..2532840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNUDV_RS12440 cysE 2523484..2524131 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  ACNUDV_RS12445 cysS 2524115..2525515 (+) 1401 WP_000631961.1 cysteine--tRNA ligase -
  ACNUDV_RS12450 - 2525508..2525912 (+) 405 WP_000370181.1 Mini-ribonuclease 3 -
  ACNUDV_RS12455 rlmB 2525920..2526666 (+) 747 WP_416764160.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  ACNUDV_RS12460 - 2526666..2527190 (+) 525 WP_000664738.1 NYN domain-containing protein -
  ACNUDV_RS12465 sigH 2527271..2527840 (+) 570 WP_000872866.1 sigma-70 family RNA polymerase sigma factor Regulator
  ACNUDV_RS12470 rpmG 2527955..2528098 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  ACNUDV_RS12475 secE 2528154..2528336 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  ACNUDV_RS12480 nusG 2528349..2528897 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  ACNUDV_RS12485 rplK 2529078..2529500 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  ACNUDV_RS12490 rplA 2529708..2530400 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  ACNUDV_RS12495 rplJ 2530672..2531172 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  ACNUDV_RS12500 rplL 2531215..2531583 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  ACNUDV_RS12505 - 2531758..2532366 (+) 609 WP_000020293.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23043.97 Da        Isoelectric Point: 9.6030

>NTDB_id=1169336 ACNUDV_RS12465 WP_000872866.1 2527271..2527840(+) (sigH) [Staphylococcus aureus isolate 23S00050-1]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRCIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1169336 ACNUDV_RS12465 WP_000872866.1 2527271..2527840(+) (sigH) [Staphylococcus aureus isolate 23S00050-1]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGATGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.413

100

0.984
  sigH Staphylococcus aureus N315

97.354

100

0.974

Multiple sequence alignment