Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   ACFCTL_RS03685 Genome accession   NZ_OZ182546
Coordinates   757330..759537 (-) Length   735 a.a.
NCBI ID   WP_027220487.1    Uniprot ID   -
Organism   Legionella pneumophila isolate ZIB8567     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 752330..764537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFCTL_RS03665 - 752836..754764 (-) 1929 WP_027220484.1 hypothetical protein -
  ACFCTL_RS03670 - 754889..755281 (-) 393 WP_011214843.1 hypothetical protein -
  ACFCTL_RS03675 - 755418..755795 (+) 378 WP_027220485.1 hypothetical protein -
  ACFCTL_RS03680 - 755997..757304 (+) 1308 WP_027220486.1 tetratricopeptide repeat protein -
  ACFCTL_RS03685 comEC 757330..759537 (-) 2208 WP_027220487.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACFCTL_RS03690 pilE 759615..760064 (-) 450 WP_027220488.1 type IV pilin protein Machinery gene
  ACFCTL_RS03695 - 760076..763585 (-) 3510 WP_027220489.1 pilus assembly protein -
  ACFCTL_RS03700 - 763598..764110 (-) 513 WP_027220490.1 pilus assembly protein -

Sequence

Protein


Download         Length: 735 a.a.        Molecular weight: 83316.83 Da        Isoelectric Point: 9.6572

>NTDB_id=1167970 ACFCTL_RS03685 WP_027220487.1 757330..759537(-) (comEC) [Legionella pneumophila isolate ZIB8567]
MEIFCFLIGVLYAYTYNIYLTIAIPLLFYITPRYPIVLFFIAGYGFALIHQWIVSPKGMPETQVITQAQLEGTIASIPMQ
RPNKTQFHFAIEKINNNPAQGLIQLNWYNKPPVLRAGQRWQFSVKLKKPRNFHNPGGFNYVSYLGARHIHWTGYIRYGNN
KLISNQPPSFSWLTLREKIGDALTKMAPDTETAGIIEALTLNVTHHISSDHWNLFRRTGTIHLFGISGEHIALVSGIFFI
VMRWIWSINYRCCLFLPANTIASIGGLLAALPYAFLAGFEPPVQRALIGCVLYTIYAIGKQRFTPWQIWRYALFLVLCIE
PHAVFLQGFYFSFLAVACLLLTHQRWPLKNYKKTLALQLSCLIGLMPLTLHWYSYGSINGFLANLFAIPLVSFLIVPLAL
MTMITSPFHWSWILMKPLAWLVALLLQGLTYVEQIAGINITWSITSVTMMLAMTAGLFLRVLLPVKPFKHLAILWIILPL
FPPRTAIYPGEALINILDVGQGLAVAIQTQHHVLLYDTGDSYFQGSDLGQMAIIPFFRSIGIKTIDKIVISHPDKDHKGG
LNSLEKEMQVNQLIVNDPYFYKRGSNCHSYPQWQWDGVSFRFLPIRESFNKKNNNSCILQVSNSAGRVLLTGDIEKAAEE
YLVRNYGSQLASEILVVPHHGSKTSSSYRFLLEVNPLYAIASLGFDNRFKFPHSKTLQSMKTLGITFFRTDECGMAEIKL
PASGKINKPTCMQAE

Nucleotide


Download         Length: 2208 bp        

>NTDB_id=1167970 ACFCTL_RS03685 WP_027220487.1 757330..759537(-) (comEC) [Legionella pneumophila isolate ZIB8567]
ATGGAAATTTTTTGCTTTTTAATAGGCGTACTTTATGCCTATACCTATAATATTTATCTAACTATTGCGATTCCTTTACT
CTTTTATATCACACCAAGATATCCCATTGTCCTGTTCTTCATCGCCGGATATGGCTTTGCCCTGATTCATCAGTGGATTG
TATCTCCCAAGGGCATGCCTGAGACGCAAGTAATCACTCAAGCCCAATTGGAAGGAACTATTGCTTCCATCCCCATGCAA
CGTCCTAACAAAACCCAATTCCATTTTGCAATTGAAAAAATTAATAATAACCCTGCTCAAGGCTTGATCCAATTAAACTG
GTATAACAAACCACCTGTCTTACGAGCCGGTCAGCGATGGCAATTTTCAGTGAAACTAAAAAAACCTCGTAACTTCCACA
ACCCGGGAGGTTTTAATTATGTAAGTTACCTGGGGGCCCGTCATATCCATTGGACTGGCTATATTCGTTATGGGAATAAT
AAGCTAATTAGCAATCAACCCCCTTCTTTCAGTTGGTTAACACTACGTGAAAAAATTGGGGATGCTTTGACAAAAATGGC
ACCGGATACAGAAACGGCAGGCATCATTGAAGCATTAACGTTAAATGTTACTCACCATATCAGTTCGGATCATTGGAATT
TGTTCCGAAGAACAGGAACGATACATTTATTCGGAATTTCAGGAGAGCACATCGCTCTGGTCTCCGGCATTTTCTTTATC
GTGATGAGATGGATTTGGTCAATAAATTATCGATGCTGTTTGTTCTTACCGGCCAATACCATAGCGAGTATCGGTGGGCT
ACTGGCCGCCTTGCCCTATGCTTTTTTAGCCGGGTTTGAGCCTCCTGTGCAACGTGCTTTAATTGGTTGTGTACTTTACA
CAATATACGCCATAGGAAAACAACGTTTTACACCATGGCAAATATGGAGATATGCCTTATTTTTAGTCTTGTGTATTGAG
CCCCATGCCGTATTCCTGCAAGGTTTTTACTTTTCATTTCTTGCCGTGGCCTGTCTTCTATTGACTCATCAACGCTGGCC
ACTGAAAAATTATAAAAAAACACTGGCATTACAATTAAGCTGCCTCATTGGATTAATGCCCTTGACTCTCCATTGGTATT
CCTATGGTTCTATCAATGGATTTCTTGCCAATTTATTCGCCATACCTTTAGTCAGTTTTCTGATAGTGCCCTTGGCTTTA
ATGACTATGATAACGAGTCCATTTCATTGGTCCTGGATATTGATGAAACCATTGGCGTGGCTTGTTGCCCTGTTACTGCA
AGGACTAACGTATGTTGAGCAAATAGCCGGGATCAATATCACCTGGTCCATCACCTCGGTAACAATGATGCTCGCTATGA
CAGCAGGTCTGTTTTTAAGGGTATTATTACCTGTCAAGCCATTCAAACACTTGGCTATCCTTTGGATTATCCTTCCCTTA
TTTCCGCCTCGTACTGCAATTTATCCAGGTGAAGCATTAATTAATATTTTGGATGTTGGGCAAGGACTTGCCGTTGCGAT
ACAAACGCAACATCATGTTTTACTCTACGATACGGGAGATTCCTATTTTCAGGGAAGTGATTTAGGGCAAATGGCGATAA
TCCCCTTTTTCAGGTCAATTGGAATAAAAACAATTGACAAAATAGTAATAAGCCATCCCGATAAAGATCATAAGGGCGGA
TTAAATTCCCTTGAAAAAGAGATGCAAGTCAATCAACTAATAGTGAATGATCCCTATTTTTATAAACGTGGAAGTAATTG
TCATTCATACCCGCAATGGCAATGGGATGGGGTGAGTTTTCGTTTTTTACCCATCAGGGAATCTTTCAATAAAAAAAATA
ACAATTCTTGTATCTTGCAGGTAAGTAATTCGGCTGGCAGGGTTTTATTAACGGGAGATATTGAAAAAGCAGCGGAGGAG
TACCTGGTAAGAAACTACGGCAGTCAGCTGGCATCCGAAATTTTAGTTGTGCCTCATCATGGGAGCAAAACGTCTTCATC
CTATCGATTTTTGCTGGAAGTAAACCCGCTTTATGCCATTGCATCTTTAGGATTTGATAATCGTTTCAAATTTCCACATT
CTAAAACTTTGCAAAGCATGAAAACATTAGGTATCACTTTTTTTAGAACAGACGAATGCGGAATGGCAGAAATCAAACTA
CCTGCGTCAGGTAAAATTAACAAACCAACCTGTATGCAGGCTGAATAA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(22-158)

Competence protein (Competence)

(199-464)

Metallo-beta-lactamase superfamily (Lactamase_B)

(498-578)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Legionella pneumophila strain Lp02

98.501

99.864

0.984
  comEC Legionella pneumophila strain ERS1305867

96.327

100

0.963

Multiple sequence alignment