Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   AB3225_RS00610 Genome accession   NZ_OZ061332
Coordinates   130753..131424 (-) Length   223 a.a.
NCBI ID   WP_004270751.1    Uniprot ID   A0A1B2A7J9
Organism   Latilactobacillus curvatus isolate Latilactobacillus curvatus J116     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 125753..136424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3225_RS00585 rpsO 126066..126335 (-) 270 WP_004271112.1 30S ribosomal protein S15 -
  AB3225_RS00590 rpsT 126612..126866 (+) 255 WP_004271117.1 30S ribosomal protein S20 -
  AB3225_RS00595 holA 126922..127950 (-) 1029 WP_076786858.1 DNA polymerase III subunit delta -
  AB3225_RS00600 comEC 127951..130065 (-) 2115 WP_367370309.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  AB3225_RS00605 - 130206..130694 (-) 489 WP_004270740.1 ComE operon protein 2 -
  AB3225_RS00610 comEA 130753..131424 (-) 672 WP_004270751.1 helix-hairpin-helix domain-containing protein Machinery gene
  AB3225_RS00615 - 131500..132546 (-) 1047 WP_080563410.1 SepM family pheromone-processing serine protease -
  AB3225_RS00620 coaD 132548..133042 (-) 495 WP_065825725.1 pantetheine-phosphate adenylyltransferase -
  AB3225_RS00625 rsmD 133054..133608 (-) 555 WP_004270750.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  AB3225_RS00630 - 133614..133904 (-) 291 WP_004270748.1 YlbG family protein -
  AB3225_RS00635 - 133924..135012 (-) 1089 WP_367370310.1 CAP-associated domain-containing protein -
  AB3225_RS00640 - 135025..136212 (-) 1188 WP_004270744.1 FtsW/RodA/SpoVE family cell cycle protein -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 24849.51 Da        Isoelectric Point: 9.9048

>NTDB_id=1165945 AB3225_RS00610 WP_004270751.1 130753..131424(-) (comEA) [Latilactobacillus curvatus isolate Latilactobacillus curvatus J116]
MWRDYWQRYRRFWWVPCLVIILLGGGVFWQHSRQQRFLSTNQQLMAQSTKRKVKAKPVKQKKSVSKGGFVDIKGAVAHPG
IYPICVAKTRLFEVLKQAGDVTEAADTSQLNLAQTLSDQLIIYVPTKGEAVQAEELVKAADEPQAATDNQAGASPISTDA
KINLNQADATQLQTLNGIGPKKAEQIIAYRDEQGQFKQIEDLQKVGGIGPKTFEQLRPQICVN

Nucleotide


Download         Length: 672 bp        

>NTDB_id=1165945 AB3225_RS00610 WP_004270751.1 130753..131424(-) (comEA) [Latilactobacillus curvatus isolate Latilactobacillus curvatus J116]
ATGTGGCGCGACTATTGGCAACGGTATCGTCGATTCTGGTGGGTACCTTGTTTGGTGATAATTTTACTTGGTGGTGGTGT
GTTTTGGCAGCATAGTCGGCAACAACGTTTTCTATCAACCAATCAACAATTGATGGCGCAATCAACTAAGCGAAAAGTGA
AGGCAAAACCCGTCAAACAGAAGAAAAGCGTCTCAAAAGGTGGGTTTGTCGATATCAAAGGCGCTGTGGCACATCCAGGG
ATTTATCCGATTTGTGTTGCAAAGACGCGTTTATTTGAGGTGCTGAAACAAGCGGGGGATGTGACCGAAGCAGCGGATAC
GAGTCAGTTGAACTTAGCGCAAACATTGAGTGACCAACTTATTATCTATGTGCCAACTAAGGGAGAAGCGGTGCAAGCCG
AAGAATTAGTGAAAGCGGCAGACGAGCCACAGGCTGCGACTGACAATCAAGCGGGAGCCAGTCCGATATCAACTGATGCT
AAAATCAACCTAAACCAAGCGGATGCGACACAATTGCAAACGCTAAATGGCATCGGTCCTAAAAAAGCTGAACAAATAAT
TGCATATCGGGATGAGCAAGGGCAGTTTAAACAAATCGAAGATCTTCAAAAAGTTGGGGGAATTGGGCCGAAAACGTTTG
AACAATTACGGCCACAAATTTGTGTTAATTAG

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(70-115)

Helix-hairpin-helix motif (HHH_3)

(160-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1B2A7J9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Latilactobacillus sakei subsp. sakei 23K

64.53

100

0.677
  comEA Lactococcus lactis subsp. cremoris KW2

36.283

100

0.368

Multiple sequence alignment