Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   ACE4RD_RS13115 Genome accession   NZ_OZ059823
Coordinates   2644902..2645888 (-) Length   328 a.a.
NCBI ID   WP_000959279.1    Uniprot ID   A0A2S6DCY7
Organism   Staphylococcus aureus isolate E2_22S00623-1     
Function   require for natural transformation (predicted from homology)   
Unclear

Genomic Context

Location: 2639902..2650888
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE4RD_RS13090 - 2640162..2640509 (-) 348 WP_001242104.1 hypothetical protein -
  ACE4RD_RS13095 - 2640695..2641288 (+) 594 WP_000224612.1 CYTH domain-containing protein -
  ACE4RD_RS13100 - 2641392..2641757 (+) 366 WP_000214070.1 truncated hemoglobin YjbI -
  ACE4RD_RS13105 yjbH 2641780..2642586 (+) 807 WP_000896695.1 protease adaptor protein YjbH -
  ACE4RD_RS13110 pepF 2643046..2644854 (-) 1809 WP_000082727.1 oligoendopeptidase F -
  ACE4RD_RS13115 coiA 2644902..2645888 (-) 987 WP_000959279.1 competence protein CoiA Machinery gene
  ACE4RD_RS13120 mecA 2646009..2646728 (-) 720 WP_001217731.1 adaptor protein MecA -
  ACE4RD_RS13125 spxA 2647099..2647494 (-) 396 WP_000258003.1 transcriptional regulator SpxA -
  ACE4RD_RS13130 trpS 2647789..2648778 (+) 990 WP_000448934.1 tryptophan--tRNA ligase -
  ACE4RD_RS13135 - 2648898..2650520 (-) 1623 WP_000406183.1 peptide ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 328 a.a.        Molecular weight: 38800.32 Da        Isoelectric Point: 9.4277

>NTDB_id=1165359 ACE4RD_RS13115 WP_000959279.1 2644902..2645888(-) (coiA) [Staphylococcus aureus isolate E2_22S00623-1]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNESIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPISYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFQSMFINPITRKL
HTFNLEKKQIMMFQQIQYIGGHKYVAEKRNVKMSELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVHNYGYIFPEQIYIENHPIEWQLQVDLWLKNGESILVSDNLNYFKLKKFIVALESKTAIIEKLINNYLNISSDR
GNDVQILF

Nucleotide


Download         Length: 987 bp        

>NTDB_id=1165359 ACE4RD_RS13115 WP_000959279.1 2644902..2645888(-) (coiA) [Staphylococcus aureus isolate E2_22S00623-1]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGCGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCGGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAATCGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTTCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCAAAGTATGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATATAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGTCAAAATGAGTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAATTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGCACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAGAAAGCATATTAGTAAGTGACAATCTTAATTATTTTAAACTGAAAA
AGTTTATTGTTGCTCTAGAAAGTAAAACAGCGATTATAGAAAAACTTATTAACAATTATTTAAATATTAGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(6-308)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DCY7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Staphylococcus aureus N315

96.037

100

0.96
  coiA Staphylococcus aureus MW2

96.037

100

0.96

Multiple sequence alignment