Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   ACE4RD_RS12980 Genome accession   NZ_OZ059823
Coordinates   2614824..2615393 (+) Length   189 a.a.
NCBI ID   WP_000287260.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate E2_22S00623-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2609824..2620393
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE4RD_RS12950 - 2611039..2611323 (-) 285 WP_000790905.1 lactococcin 972 family bacteriocin -
  ACE4RD_RS12955 - 2611959..2612036 (-) 78 WP_099119695.1 putative holin-like toxin -
  ACE4RD_RS12960 - 2612337..2612939 (-) 603 WP_001033867.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  ACE4RD_RS12965 - 2612954..2613130 (-) 177 WP_000214898.1 YkvS family protein -
  ACE4RD_RS12970 - 2613329..2614315 (+) 987 WP_000668814.1 lipoate--protein ligase -
  ACE4RD_RS12975 - 2614396..2614614 (-) 219 WP_000876826.1 IDEAL domain-containing protein -
  ACE4RD_RS12980 comK/comK1 2614824..2615393 (+) 570 WP_000287260.1 competence protein ComK Regulator
  ACE4RD_RS12995 - 2615880..2617391 (-) 1512 WP_000414168.1 bifunctional UDP-sugar hydrolase/5'-nucleotidase -
  ACE4RD_RS13000 - 2617530..2618888 (-) 1359 WP_000021872.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 22624.86 Da        Isoelectric Point: 9.6092

>NTDB_id=1165358 ACE4RD_RS12980 WP_000287260.1 2614824..2615393(+) (comK/comK1) [Staphylococcus aureus isolate E2_22S00623-1]
MYSQNIYVIRKGDMVIRPAFDDDDQRHGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1165358 ACE4RD_RS12980 WP_000287260.1 2614824..2615393(+) (comK/comK1) [Staphylococcus aureus isolate E2_22S00623-1]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGACA
TGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATCAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTT
CATACCACAGTTTATGGCATCAATATAACAATTCCATTTTTTACTATTACATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains

Predicted by InterproScan.

ComK protein (ComK)

(5-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

99.471

100

0.995
  comK/comK1 Staphylococcus aureus N315

99.471

100

0.995

Multiple sequence alignment