Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACKU4C_RS04210 Genome accession   NZ_OY781470
Coordinates   851043..852875 (-) Length   610 a.a.
NCBI ID   WP_321314709.1    Uniprot ID   -
Organism   MAG: Halarcobacter sp. isolate 3fe945d7-d765-420f-81cf-5f3e3ea35e3e     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 846043..857875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKU4C_RS04185 (U2967_RS04185) - 846822..847874 (-) 1053 WP_321314700.1 succinylglutamate desuccinylase/aspartoacylase family protein -
  ACKU4C_RS04190 (U2967_RS04190) rimK 847878..848819 (-) 942 WP_321314702.1 30S ribosomal protein S6--L-glutamate ligase -
  ACKU4C_RS04195 (U2967_RS04195) - 848820..849248 (-) 429 WP_321314704.1 RimK/LysX family protein -
  ACKU4C_RS04200 (U2967_RS04200) - 849351..850016 (-) 666 WP_321314706.1 tetratricopeptide repeat protein -
  ACKU4C_RS04205 (U2967_RS04205) - 850016..851038 (-) 1023 WP_321314707.1 alanine racemase -
  ACKU4C_RS04210 (U2967_RS04210) uvrC 851043..852875 (-) 1833 WP_321314709.1 excinuclease ABC subunit UvrC Machinery gene
  ACKU4C_RS04215 (U2967_RS04215) - 853175..854902 (+) 1728 WP_321314711.1 ATP-binding protein -
  ACKU4C_RS04220 (U2967_RS04220) - 854899..855843 (-) 945 WP_321314712.1 HAMP domain-containing sensor histidine kinase -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 71367.85 Da        Isoelectric Point: 9.2992

>NTDB_id=1161822 ACKU4C_RS04210 WP_321314709.1 851043..852875(-) (uvrC) [MAG: Halarcobacter sp. isolate 3fe945d7-d765-420f-81cf-5f3e3ea35e3e]
MNLEEKLKQLPNEAGVYQYFDEKGKLLYIGKAKILKNRVKSYFKFTPKLLPADKLSPRIYKMITEVKSLEWIVVPNEHDA
LILENSLIKQLKPKYNILLRDDKTYPYIYINFNENFPRLEITRRVLKEKNIKYFGPYSTGARDMLDSIYEIVPLVQKKSC
IKGKEACLFYQIKKCFAPCEGKISKEEYSKLVDNALNYIYNKNKLISKLTKKMEEYSNEFRFEEAMKLRDRIKTIEKSQI
QTGMDLATNENIDLFAIKIKDTKAVLVRMFFRDGKLASSNHNYIKPNKEDITIDIQEAYERAIINYYDNEIPVLPDEIII
TTELEEKDEIENFIKEKFSKKIPIITPKRGKKKEILNVALDNCNELLRLSSVKDTSSVYSQLKQLFNLDKVPNRFECFDN
SHMMGQATVGAMVTWEEKFEKGDFRHYNLESKDEYSQMRETLLRRVESFEKNPAPDMWVIDGGETLLKLAIDIRNSCGVN
LDIVAIAKEKLDFKAHRAKGSAKDIIFFENNGIVEKLDLLPSDKRLQFIQRLRDEAHRFAISFHKKQKRKEDTQISLLQI
KGIGEAKMKKLLLYFGTFENIKNSSLEELKDVLNEKDAMLIINYFKTLEG

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=1161822 ACKU4C_RS04210 WP_321314709.1 851043..852875(-) (uvrC) [MAG: Halarcobacter sp. isolate 3fe945d7-d765-420f-81cf-5f3e3ea35e3e]
ATGAATTTAGAAGAGAAATTAAAACAACTACCAAATGAAGCTGGAGTTTATCAATATTTTGATGAAAAAGGTAAACTTTT
ATATATAGGAAAAGCAAAAATTTTAAAAAATAGAGTTAAATCTTATTTTAAATTTACTCCAAAACTACTACCAGCAGATA
AACTAAGTCCACGTATATATAAAATGATAACAGAGGTTAAATCATTAGAATGGATAGTTGTACCAAATGAACATGATGCT
TTAATTTTAGAAAATTCTCTTATAAAACAACTAAAACCAAAATACAATATATTACTTCGTGATGATAAAACATATCCTTA
TATTTATATAAATTTCAATGAAAACTTTCCAAGACTTGAAATTACAAGAAGAGTATTAAAAGAAAAAAATATTAAATATT
TTGGTCCCTACTCTACTGGTGCTAGAGATATGCTAGATTCTATATATGAAATAGTTCCTTTAGTACAAAAAAAATCTTGT
ATCAAAGGTAAAGAAGCTTGTCTTTTTTATCAAATAAAAAAATGTTTTGCACCATGTGAAGGGAAAATTTCAAAAGAAGA
GTATTCAAAATTAGTTGATAATGCTTTAAATTACATTTACAATAAAAATAAACTTATCTCCAAACTAACAAAAAAAATGG
AAGAATATAGCAATGAGTTTAGATTTGAAGAAGCTATGAAATTAAGAGATAGGATAAAAACTATTGAAAAATCTCAAATA
CAAACTGGTATGGATTTAGCTACAAATGAAAATATTGATCTTTTCGCAATAAAAATAAAAGATACAAAAGCGGTACTAGT
AAGAATGTTTTTTAGGGATGGGAAATTAGCTTCTAGTAATCACAACTATATAAAGCCAAATAAAGAAGATATTACTATCG
ATATACAAGAAGCTTACGAAAGAGCTATAATTAACTACTATGATAATGAAATCCCTGTTTTACCTGATGAGATTATCATT
ACAACAGAATTAGAAGAAAAAGATGAAATTGAAAACTTTATAAAAGAAAAATTCTCTAAAAAAATACCAATTATAACACC
AAAAAGAGGAAAGAAAAAAGAGATTTTAAATGTCGCATTAGATAATTGTAATGAGCTATTAAGACTCTCTTCCGTAAAAG
ATACAAGCTCAGTATATTCACAATTAAAACAATTATTCAATCTTGATAAAGTTCCTAATAGATTTGAATGCTTTGATAAT
TCACATATGATGGGACAAGCTACTGTAGGAGCTATGGTAACATGGGAAGAGAAATTTGAAAAAGGTGATTTTAGACATTA
TAATCTAGAATCAAAAGATGAATACTCTCAAATGAGAGAAACTCTATTAAGAAGAGTAGAAAGTTTTGAAAAAAACCCCG
CACCAGATATGTGGGTCATAGATGGAGGTGAAACTCTTCTTAAACTTGCAATTGATATTAGAAACTCATGTGGAGTAAAT
TTAGATATTGTAGCAATTGCAAAAGAGAAATTAGACTTTAAAGCTCATAGAGCAAAAGGTAGTGCAAAAGATATTATATT
TTTTGAAAACAATGGTATAGTTGAAAAGTTAGATTTACTTCCTAGTGATAAACGTCTACAATTTATACAAAGATTAAGAG
ATGAGGCGCATAGATTTGCTATATCATTTCATAAAAAACAAAAAAGAAAAGAAGATACACAAATCTCTTTATTACAAATC
AAAGGTATAGGTGAAGCAAAAATGAAAAAACTTCTTTTATATTTTGGAACATTTGAAAATATAAAAAACTCTTCTTTAGA
AGAATTAAAAGATGTTCTAAACGAAAAAGATGCTATGCTTATAATAAATTATTTTAAAACTCTTGAAGGTTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(14-96)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-541)

UvrB/uvrC motif (UVR)

(204-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

49.331

98.033

0.484

Multiple sequence alignment