Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   U8955_RS02000 Genome accession   NZ_OY769914
Coordinates   384131..384820 (+) Length   229 a.a.
NCBI ID   WP_038804114.1    Uniprot ID   -
Organism   Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 379131..389820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U8955_RS01975 (SDENT7746_02005) gpsB 379170..379499 (+) 330 WP_038804118.1 cell division regulator GpsB -
  U8955_RS01985 (SDENT7746_02015) - 379986..381143 (+) 1158 WP_038804117.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  U8955_RS01990 (SDENT7746_02020) mapZ 381156..382619 (+) 1464 WP_038804116.1 cell division site-positioning protein MapZ -
  U8955_RS01995 (SDENT7746_02025) gndA 382695..384119 (+) 1425 WP_038804115.1 NADP-dependent phosphogluconate dehydrogenase -
  U8955_RS02000 (SDENT7746_02030) covR 384131..384820 (+) 690 WP_038804114.1 response regulator transcription factor Regulator
  U8955_RS02005 (SDENT7746_02035) - 384919..385899 (+) 981 WP_038804113.1 N-acetylmuramoyl-L-alanine amidase family protein -
  U8955_RS02010 (SDENT7746_02040) mvk 386017..386895 (+) 879 WP_038804112.1 mevalonate kinase -
  U8955_RS02015 (SDENT7746_02045) mvaD 386877..387830 (+) 954 WP_038804110.1 diphosphomevalonate decarboxylase -
  U8955_RS02020 (SDENT7746_02050) - 387817..388824 (+) 1008 WP_038804109.1 phosphomevalonate kinase -
  U8955_RS02025 (SDENT7746_02055) fni 388808..389809 (+) 1002 WP_038804108.1 type 2 isopentenyl-diphosphate Delta-isomerase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26713.88 Da        Isoelectric Point: 8.0259

>NTDB_id=1161708 U8955_RS02000 WP_038804114.1 384131..384820(+) (covR) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGGKALSMALQTDYDLILLNARLGDMTAQDFADKLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDQLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1161708 U8955_RS02000 WP_038804114.1 384131..384820(+) (covR) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTCGAGGAGGGGGGAAAAGCCCTCTCCATGGCTCTCCAGACAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCCCAGGATTTTGCAGACAAGCTGAGTCGGACAAAACCTGCCTCAGTGATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATCAGCTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACACTGTAGTCAGATGAAGGTCC
CAACGTCTTACCGCAATTTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTGTTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACTAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGGTATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.491

99.563

0.463

Multiple sequence alignment