Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACI6O7_RS09350 Genome accession   NZ_OY725152
Coordinates   1905101..1905802 (-) Length   233 a.a.
NCBI ID   WP_004255173.1    Uniprot ID   S6FFV7
Organism   Lactococcus lactis strain IMDO WA12L8     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1900101..1910802
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI6O7_RS09330 (LLWA12L8_FAMOGCFE_01873) - 1900211..1901428 (-) 1218 WP_404378302.1 cysteine desulfurase -
  ACI6O7_RS09335 (LLWA12L8_FAMOGCFE_01874) sufD 1901428..1902684 (-) 1257 WP_015426954.1 Fe-S cluster assembly protein SufD -
  ACI6O7_RS09340 (LLWA12L8_FAMOGCFE_01875) sufC 1902822..1903592 (-) 771 WP_004255181.1 Fe-S cluster assembly ATPase SufC -
  ACI6O7_RS09345 (LLWA12L8_FAMOGCFE_01876) - 1903767..1905098 (-) 1332 WP_021722251.1 glycosyltransferase family 4 protein -
  ACI6O7_RS09350 (LLWA12L8_FAMOGCFE_01877) mecA 1905101..1905802 (-) 702 WP_004255173.1 adaptor protein MecA Regulator
  ACI6O7_RS09355 (LLWA12L8_FAMOGCFE_01878) - 1905932..1906666 (-) 735 WP_404378303.1 amino acid ABC transporter ATP-binding protein -
  ACI6O7_RS09360 (LLWA12L8_FAMOGCFE_01879) - 1906666..1907352 (-) 687 WP_004255158.1 amino acid ABC transporter permease -
  ACI6O7_RS09365 (LLWA12L8_FAMOGCFE_01880) - 1907499..1908407 (-) 909 WP_404378304.1 diacylglycerol/lipid kinase family protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27077.46 Da        Isoelectric Point: 4.1246

>NTDB_id=1160546 ACI6O7_RS09350 WP_004255173.1 1905101..1905802(-) (mecA) [Lactococcus lactis strain IMDO WA12L8]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=1160546 ACI6O7_RS09350 WP_004255173.1 1905101..1905802(-) (mecA) [Lactococcus lactis strain IMDO WA12L8]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGACATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTTATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGCT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCAATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCGTTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTCGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGCAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FFV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

99.571

100

0.996
  mecA Lactococcus lactis subsp. cremoris KW2

96.996

100

0.97

Multiple sequence alignment