Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   QOR62_RS06815 Genome accession   NZ_OX460940
Coordinates   1331969..1333195 (-) Length   408 a.a.
NCBI ID   WP_000918412.1    Uniprot ID   A0AAV3JKF5
Organism   Streptococcus agalactiae isolate MRI Z2-179     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1311889..1331958 1331969..1333195 flank 11


Gene organization within MGE regions


Location: 1311889..1333195
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QOR62_RS06700 - 1311889..1314240 (-) 2352 WP_000734146.1 VirB4-like conjugal transfer ATPase, CD1110 family -
  QOR62_RS06705 - 1314197..1314550 (-) 354 WP_001097574.1 PrgI family mobile element protein -
  QOR62_RS06710 - 1314612..1315466 (-) 855 WP_000980129.1 hypothetical protein -
  QOR62_RS06715 - 1315485..1315727 (-) 243 WP_001072178.1 hypothetical protein -
  QOR62_RS06720 - 1315745..1317562 (-) 1818 WP_000287324.1 VirD4-like conjugal transfer protein, CD1115 family -
  QOR62_RS06725 - 1317562..1318050 (-) 489 WP_000093695.1 hypothetical protein -
  QOR62_RS06730 - 1318127..1318711 (-) 585 WP_000619442.1 CPBP family intramembrane glutamic endopeptidase -
  QOR62_RS06735 - 1318714..1318947 (-) 234 WP_001005706.1 hypothetical protein -
  QOR62_RS06740 - 1318956..1319339 (-) 384 WP_000895332.1 hypothetical protein -
  QOR62_RS06745 - 1319350..1319778 (-) 429 WP_001050381.1 hypothetical protein -
  QOR62_RS06750 dcm 1319762..1321117 (-) 1356 WP_000670054.1 DNA (cytosine-5-)-methyltransferase -
  QOR62_RS06755 - 1321266..1322084 (-) 819 WP_000822793.1 replication initiator protein A -
  QOR62_RS06760 - 1322081..1322254 (-) 174 WP_001169693.1 hypothetical protein -
  QOR62_RS06765 rplL 1322469..1322834 (-) 366 WP_001196976.1 50S ribosomal protein L7/L12 -
  QOR62_RS06770 rplJ 1322898..1323398 (-) 501 WP_001287285.1 50S ribosomal protein L10 -
  QOR62_RS06775 - 1323832..1325940 (+) 2109 WP_000002806.1 ATP-dependent Clp protease ATP-binding subunit -
  QOR62_RS06780 mmuM 1326033..1326977 (-) 945 WP_000532341.1 homocysteine S-methyltransferase -
  QOR62_RS06785 - 1326982..1328358 (-) 1377 WP_000427480.1 amino acid permease -
  QOR62_RS06790 - 1328488..1329138 (-) 651 WP_000120090.1 HXXEE domain-containing protein -
  QOR62_RS06795 - 1329296..1329619 (-) 324 WP_000959713.1 HXXEE domain-containing protein -
  QOR62_RS06805 - 1330752..1331381 (+) 630 WP_000140673.1 TetR/AcrR family transcriptional regulator -
  QOR62_RS06810 yihA 1331362..1331958 (-) 597 WP_000796925.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  QOR62_RS06815 clpX 1331969..1333195 (-) 1227 WP_000918412.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44850.28 Da        Isoelectric Point: 4.4424

>NTDB_id=1159096 QOR62_RS06815 WP_000918412.1 1331969..1333195(-) (clpX) [Streptococcus agalactiae isolate MRI Z2-179]
MAGNRNNDMNVYCSFCGKSQDEVKKIIAGNGVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLEILNQYVVGQDR
AKRALAVAVYNHYKRVSYTESSDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTKN
ILFIVGGAFDGIEDLVKQRLGEKIIGFGQTSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALELLTAEDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALLAIADKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEGT
DKPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1159096 QOR62_RS06815 WP_000918412.1 1331969..1333195(-) (clpX) [Streptococcus agalactiae isolate MRI Z2-179]
ATGGCTGGGAATCGTAATAACGATATGAATGTCTATTGTTCATTTTGTGGCAAAAGCCAAGATGAAGTAAAAAAAATTAT
TGCAGGTAATGGTGTTTTCATTTGTAATGAATGTGTGGCCTTATCACAAGAAATTATTAAGGAAGAATTAGCTGAGGAAG
TACTTGCTGATTTAGCAGAAGTACCAAAACCTAAGGAACTATTAGAAATATTAAATCAATATGTTGTAGGGCAAGATCGT
GCTAAACGTGCTTTAGCAGTTGCTGTCTACAATCATTACAAGCGTGTTAGTTATACCGAGAGTAGTGACGATGATGTAGA
TTTGCAAAAATCCAACATTTTGATGATTGGTCCAACTGGCTCAGGAAAAACCTTCTTAGCACAAACACTAGCTAAAAGCC
TTAATGTACCGTTTGCTATTGCAGATGCGACTTCATTGACCGAAGCAGGATACGTTGGAGAAGATGTTGAGAATATTCTT
CTTAAATTGATTCAAGCTGCTGATTATAATGTCGAACGTGCTGAGCGTGGTATTATCTACGTTGATGAAATAGATAAAAT
TGCTAAGAAAGGCGAAAATGTTTCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTATTG
AGGGTACGGTAGCAAGTGTTCCCCCACAGGGTGGGCGTAAACATCCTAACCAAGAAATGATTCAAATTAATACCAAGAAC
ATCCTTTTTATTGTCGGTGGTGCTTTTGATGGTATTGAAGACCTTGTGAAGCAACGTTTAGGCGAAAAAATTATTGGTTT
TGGACAGACAAGCCGCAAAATTGATGACAACGCTTCTTATATGCAAGAGATAATTTCTGAGGATATTCAAAAGTTTGGAC
TGATTCCAGAGTTTATTGGCCGTTTACCAGTAGTTGCAGCGTTAGAACTTCTTACTGCAGAAGATCTGGTTCGTATTCTG
ACAGAACCACGCAATGCTTTGGTTAAACAATACCAAACCTTATTATCTTATGATGGTGTAGAATTGGAATTTGATCAGGA
TGCTCTATTGGCTATCGCTGATAAGGCTATCGAGCGCAAGACTGGTGCACGTGGTTTACGTTCTATTATTGAAGAAACGA
TGCTTGATATCATGTTTGAAATTCCAAGCCAAGAAGATGTAACAAAAGTTCGTATCACAAAGGCTGCTGTTGAGGGTACT
GACAAGCCTGTTTTAGAGACGGCTTAG

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-390)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

90.709

100

0.909
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58

98.039

0.569

Multiple sequence alignment