Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   QNH74_RS01845 Genome accession   NZ_OX352806
Coordinates   369914..370603 (+) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis isolate 861160_dxerD_hsdSA     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 364914..375603
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QNH74_RS01820 - 365243..366586 (+) 1344 WP_074390039.1 DEAD/DEAH box helicase -
  QNH74_RS01825 - 366604..366828 (+) 225 WP_002936682.1 DUF4059 family protein -
  QNH74_RS01830 trxB 366842..367759 (+) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  QNH74_RS01835 - 367769..368308 (+) 540 WP_024385904.1 DUF177 domain-containing protein -
  QNH74_RS01840 gndA 368405..369832 (+) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  QNH74_RS01845 covR 369914..370603 (+) 690 WP_012027645.1 winged helix-turn-helix domain-containing protein Regulator
  QNH74_RS01850 - 370693..371823 (+) 1131 WP_014636113.1 AI-2E family transporter -
  QNH74_RS01855 nrdR 371895..372386 (+) 492 WP_002938341.1 transcriptional regulator NrdR -
  QNH74_RS01860 - 372373..373524 (+) 1152 WP_029174426.1 replication initiation/membrane attachment protein -
  QNH74_RS01865 dnaI 373524..374423 (+) 900 WP_029174425.1 primosomal protein DnaI -
  QNH74_RS01870 - 374420..375133 (+) 714 WP_053861635.1 NADPH-dependent oxidoreductase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=1155351 QNH74_RS01845 WP_012027645.1 369914..370603(+) (covR) [Streptococcus suis isolate 861160_dxerD_hsdSA]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1155351 QNH74_RS01845 WP_012027645.1 369914..370603(+) (covR) [Streptococcus suis isolate 861160_dxerD_hsdSA]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACTGAAGTTAGTCAATATGGGGAGGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment