Detailed information    

insolico Bioinformatically predicted

Overview


Name   comK/comK1   Type   Regulator
Locus tag   OOL12_RS02865 Genome accession   NZ_OX344719
Coordinates   528068..528637 (-) Length   189 a.a.
NCBI ID   WP_000287265.1    Uniprot ID   A0A7U7EXU5
Organism   Staphylococcus aureus strain ST20190863 isolate ST20190863     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context


Location: 523068..533637
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OOL12_RS02845 - 524573..525931 (+) 1359 WP_000021864.1 TrkH family potassium uptake protein -
  OOL12_RS02850 - 526070..527581 (+) 1512 WP_000414177.1 bifunctional metallophosphatase/5'-nucleotidase -
  OOL12_RS02865 comK/comK1 528068..528637 (-) 570 WP_000287265.1 competence protein ComK Regulator
  OOL12_RS02870 - 528847..529065 (+) 219 WP_000876826.1 IDEAL domain-containing protein -
  OOL12_RS02875 - 529146..530132 (-) 987 WP_000668820.1 lipoate--protein ligase -
  OOL12_RS02880 - 530331..530507 (+) 177 WP_000214898.1 YkvS family protein -
  OOL12_RS02885 - 530522..531124 (+) 603 WP_001033867.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  OOL12_RS02890 - 531440..531502 (+) 63 WP_228764722.1 hypothetical protein -
  OOL12_RS02895 - 532041..532142 (+) 102 WP_053865031.1 hypothetical protein -
  OOL12_RS02900 - 532152..532424 (+) 273 WP_001790097.1 lactococcin 972 family bacteriocin -

Sequence


Protein


Download         Length: 189 a.a.        Molecular weight: 22601.83 Da        Isoelectric Point: 9.6091

>NTDB_id=1154824 OOL12_RS02865 WP_000287265.1 528068..528637(-) (comK/comK1) [Staphylococcus aureus strain ST20190863 isolate ST20190863]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1154824 OOL12_RS02865 WP_000287265.1 528068..528637(-) (comK/comK1) [Staphylococcus aureus strain ST20190863 isolate ST20190863]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
CGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTT
CATACCACAGTTTATGGCATCAATATAACAATTCCATTTTTTACTATTACATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains


Predicted by InterproScan.

(5-156)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A7U7EXU5

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

100

100

1

  comK/comK1 Staphylococcus aureus N315

100

100

1


Multiple sequence alignment