Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   AD178_RS07550 Genome accession   NZ_OX244288
Coordinates   1485955..1487187 (-) Length   410 a.a.
NCBI ID   WP_000106346.1    Uniprot ID   A0A064C077
Organism   Streptococcus pneumoniae strain PT8105 isolate 2RLC4     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1480955..1492187
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AD178_RS07520 (SAMEA1463109_01520) - 1481142..1482110 (+) 969 WP_000081007.1 NAD(P)/FAD-dependent oxidoreductase -
  AD178_RS07525 (SAMEA1463109_01521) whiA 1482144..1483055 (-) 912 WP_000011279.1 DNA-binding protein WhiA -
  AD178_RS07530 (SAMEA1463109_01522) - 1483052..1484029 (-) 978 WP_001231086.1 YvcK family protein -
  AD178_RS07535 (SAMEA1463109_01523) rapZ 1484026..1484916 (-) 891 WP_000163035.1 RNase adapter RapZ -
  AD178_RS07540 (SAMEA1463109_01524) - 1484968..1485348 (-) 381 WP_001140412.1 RidA family protein -
  AD178_RS07545 (SAMEA1463109_01525) yihA 1485359..1485946 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  AD178_RS07550 (SAMEA1463109_01526) clpX 1485955..1487187 (-) 1233 WP_000106346.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  AD178_RS07555 (SAMEA1463109_01527) - 1487219..1487389 (-) 171 WP_000442275.1 hypothetical protein -
  AD178_RS07560 (SAMEA1463109_01528) - 1487389..1487895 (-) 507 WP_000162472.1 dihydrofolate reductase -
  AD178_RS07565 (SAMEA1463109_01529) - 1488022..1488540 (-) 519 WP_000229866.1 Dps family protein -
  AD178_RS07570 (SAMEA1463109_01530) lytC 1489036..1490540 (-) 1505 Protein_1502 choline binding-anchored murein hydrolase LytC -
  AD178_RS07575 (SAMEA1463109_01532) tpiA 1490578..1491336 (-) 759 WP_000087897.1 triose-phosphate isomerase -
  AD178_RS07580 (SAMEA1463109_01533) - 1491434..1492111 (-) 678 WP_000221583.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45798.35 Da        Isoelectric Point: 4.4550

>NTDB_id=1154330 AD178_RS07550 WP_000106346.1 1485955..1487187(-) (clpX) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=1154330 AD178_RS07550 WP_000106346.1 1485955..1487187(-) (clpX) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATACTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A064C077

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561

Multiple sequence alignment