Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   AD178_RS06020 Genome accession   NZ_OX244288
Coordinates   1187427..1188236 (-) Length   269 a.a.
NCBI ID   WP_044814286.1    Uniprot ID   A0A822Q610
Organism   Streptococcus pneumoniae strain PT8105 isolate 2RLC4     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1182427..1193236
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AD178_RS06000 (SAMEA1463109_01212) - 1184769..1185755 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  AD178_RS06005 (SAMEA1463109_01213) - 1186018..1186791 (-) 774 WP_000731128.1 ion channel -
  AD178_RS06010 (SAMEA1463109_01214) - 1186838..1187092 (-) 255 WP_001812387.1 type II toxin-antitoxin system RelE/ParE family toxin -
  AD178_RS06015 (SAMEA1463109_01215) relB 1187094..1187336 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  AD178_RS06020 (SAMEA1463109_01216) vicX 1187427..1188236 (-) 810 WP_044814286.1 MBL fold metallo-hydrolase Regulator
  AD178_RS06025 (SAMEA1463109_01217) micB 1188238..1189587 (-) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  AD178_RS06030 (SAMEA1463109_01218) micA 1189580..1190284 (-) 705 WP_000722076.1 response regulator YycF Regulator
  AD178_RS06035 (SAMEA1463109_01219) mutY 1190339..1191514 (-) 1176 WP_000886145.1 A/G-specific adenine glycosylase -
  AD178_RS06040 - 1191611..1191736 (+) 126 WP_001818232.1 hypothetical protein -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29944.94 Da        Isoelectric Point: 6.1743

>NTDB_id=1154322 AD178_RS06020 WP_044814286.1 1187427..1188236(-) (vicX) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYVWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=1154322 AD178_RS06020 WP_044814286.1 1187427..1188236(-) (vicX) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGCTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGTTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A822Q610

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773

Multiple sequence alignment