Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AD178_RS02110 Genome accession   NZ_OX244288
Coordinates   394916..395605 (+) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain PT8105 isolate 2RLC4     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 389916..400605
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AD178_RS02085 (SAMEA1463109_00417) gpsB 390013..390354 (+) 342 WP_000200644.1 cell division regulator GpsB -
  AD178_RS02095 (SAMEA1463109_00419) - 390840..391997 (+) 1158 WP_000711394.1 class I SAM-dependent RNA methyltransferase -
  AD178_RS02100 (SAMEA1463109_00420) mapZ 392010..393404 (+) 1395 WP_000039282.1 mid-cell-anchored protein MapZ -
  AD178_RS02105 (SAMEA1463109_00421) gndA 393480..394904 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  AD178_RS02110 (SAMEA1463109_00422) covR 394916..395605 (+) 690 WP_000518008.1 response regulator transcription factor Regulator
  AD178_RS02115 (SAMEA1463109_00423) cbpC 395703..396728 (+) 1026 WP_000771094.1 choline-binding protein CbpC -
  AD178_RS02120 (SAMEA1463109_00424) - 396747..397622 (+) 876 WP_000771136.1 choline-binding protein CbpJ -
  AD178_RS02125 (SAMEA1463109_00425) - 397740..398972 (-) 1233 WP_000765671.1 MFS transporter -
  AD178_RS02130 (SAMEA1463109_00426) - 398983..399603 (-) 621 WP_000153866.1 lanthionine synthetase LanC family protein -
  AD178_RS02135 - 399503..399892 (-) 390 WP_196301600.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=1154306 AD178_RS02110 WP_000518008.1 394916..395605(+) (covR) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1154306 AD178_RS02110 WP_000518008.1 394916..395605(+) (covR) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment