Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   NBW44_RS01120 Genome accession   NZ_OW724079
Coordinates   198303..198992 (+) Length   229 a.a.
NCBI ID   WP_250306849.1    Uniprot ID   -
Organism   Streptococcus sp. Marseille-Q3533     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 193303..203992
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NBW44_RS01095 gpsB 193351..193680 (+) 330 WP_312847906.1 cell division regulator GpsB -
  NBW44_RS01105 - 194162..195331 (+) 1170 WP_250306846.1 class I SAM-dependent RNA methyltransferase -
  NBW44_RS01110 - 195333..196790 (+) 1458 WP_250306847.1 cell division site-positioning protein MapZ family protein -
  NBW44_RS01115 gndA 196866..198290 (+) 1425 WP_250306848.1 NADP-dependent phosphogluconate dehydrogenase -
  NBW44_RS01120 covR 198303..198992 (+) 690 WP_250306849.1 response regulator transcription factor Regulator
  NBW44_RS01125 mvk 199234..200112 (+) 879 WP_250306850.1 mevalonate kinase -
  NBW44_RS01130 mvaD 200094..201047 (+) 954 WP_250306851.1 diphosphomevalonate decarboxylase -
  NBW44_RS01135 - 201034..202047 (+) 1014 WP_250306852.1 phosphomevalonate kinase -
  NBW44_RS01140 fni 202025..203026 (+) 1002 WP_250306853.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  NBW44_RS01145 liaF 203125..203823 (+) 699 WP_250306854.1 cell wall-active antibiotics response protein LiaF -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26490.69 Da        Isoelectric Point: 6.6519

>NTDB_id=1152580 NBW44_RS01120 WP_250306849.1 198303..198992(+) (covR) [Streptococcus sp. Marseille-Q3533]
MGKRILLLEKEKSLAHFLSLELQKEHYRVDLAEKGQKALSMALQTDYDLILLNVNLGDMTAQEFADKLSLTKPASVIMVL
DHLEDLQDVLEVVQRFAVSYIYKPVIIENLVERISAIFRGRDFIDQHCGQMKIPTSYRNLRIDVANHTVYRGDELIVLTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKIDVEGQKSYIKTVRGVGYTMQD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1152580 NBW44_RS01120 WP_250306849.1 198303..198992(+) (covR) [Streptococcus sp. Marseille-Q3533]
ATGGGGAAACGGATTTTATTACTTGAAAAAGAAAAAAGTCTAGCTCATTTTTTAAGTTTAGAACTCCAAAAAGAGCATTA
CCGAGTTGATCTGGCAGAAAAAGGGCAAAAAGCTCTTTCCATGGCTCTTCAAACAGATTATGATTTGATTTTATTAAATG
TTAATCTGGGAGATATGACAGCGCAGGAATTTGCAGACAAATTAAGTCTAACAAAACCTGCATCTGTCATCATGGTTTTA
GATCACTTAGAAGATTTGCAAGATGTGTTAGAAGTTGTTCAACGCTTTGCAGTTTCATACATCTATAAACCAGTGATTAT
TGAAAATTTGGTAGAGCGAATTTCAGCTATTTTCCGTGGCCGTGATTTTATCGACCAACATTGTGGTCAAATGAAGATAC
CCACCAGCTATCGAAATCTTAGGATAGATGTTGCCAATCATACAGTCTATCGTGGAGATGAGTTGATTGTTCTCACACGT
CGAGAATATGATCTTCTGGCTACGCTTATGGGTAGTAAAAAAGTATTGACTCGTGAGCAATTACTGGAAAGTGTCTGGAA
GTATGAAAGTGCCACAGAAACCAATATTGTAGATGTTTATATCCGATATCTACGTAGTAAAATTGATGTGGAAGGTCAAA
AAAGCTATATCAAAACAGTTCGTGGTGTAGGTTATACCATGCAGGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

50

100

0.502
  covR Lactococcus lactis subsp. lactis strain DGCC12653

47.807

99.563

0.476

Multiple sequence alignment