Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   MMH06_RS06305 Genome accession   NZ_OV904788
Coordinates   1186906..1188138 (+) Length   410 a.a.
NCBI ID   WP_240281728.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain RMV7 isolate RMV7domi     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1181906..1193138
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MMH06_RS06275 (IONPJBJN_01231) - 1181969..1182646 (+) 678 WP_000221584.1 DnaD domain-containing protein -
  MMH06_RS06280 (IONPJBJN_01232) tpiA 1182745..1183503 (+) 759 WP_000087897.1 triose-phosphate isomerase -
  MMH06_RS06285 (IONPJBJN_01233) lytC 1183541..1185046 (+) 1506 WP_013193470.1 choline binding-anchored murein hydrolase LytC -
  MMH06_RS06290 (IONPJBJN_01234) - 1185543..1186061 (+) 519 WP_000229868.1 Dps family protein -
  MMH06_RS06295 (IONPJBJN_01235) - 1186193..1186699 (+) 507 WP_000162475.1 dihydrofolate reductase -
  MMH06_RS06300 (IONPJBJN_01236) - 1186699..1186869 (+) 171 WP_000442260.1 hypothetical protein -
  MMH06_RS06305 (IONPJBJN_01237) clpX 1186906..1188138 (+) 1233 WP_240281728.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  MMH06_RS06310 (IONPJBJN_01238) yihA 1188147..1188734 (+) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  MMH06_RS06315 (IONPJBJN_01239) - 1188745..1189125 (+) 381 WP_001140412.1 RidA family protein -
  MMH06_RS06320 (IONPJBJN_01240) rapZ 1189177..1190067 (+) 891 WP_000163033.1 RNase adapter RapZ -
  MMH06_RS06325 (IONPJBJN_01241) - 1190064..1191041 (+) 978 WP_001231086.1 YvcK family protein -
  MMH06_RS06330 (IONPJBJN_01242) whiA 1191038..1191949 (+) 912 WP_000011306.1 DNA-binding protein WhiA -
  MMH06_RS06335 (IONPJBJN_01243) - 1191983..1192951 (-) 969 WP_000081004.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45681.29 Da        Isoelectric Point: 4.5042

>NTDB_id=1152115 MMH06_RS06305 WP_240281728.1 1186906..1188138(+) (clpX) [Streptococcus pneumoniae strain RMV7 isolate RMV7domi]
MPTTRNNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIAAATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELKFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=1152115 MMH06_RS06305 WP_240281728.1 1186906..1188138(+) (clpX) [Streptococcus pneumoniae strain RMV7 isolate RMV7domi]
ATGCCTACAACTAGGAATAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAGCCAAGAAGAAGTACAAAAAATAAT
CGCAGGGAACAACGCCTTTATCTGTAATGAATGTGTGGAGTTAGCCCAGGAAATCATTCGTGAGGAGTTGGCTGAGGAAG
TTTTGGCAGACTTGTCTGAAGTTCCAAAACCAATCGAACTTCTCCATATCTTGAACCACTATGTAATCGGTCAAGATCGT
GCCAAACGGGCCTTAGCAGTGGCGGTTTACAACCACTACAAACGCATCAATTTCCACGATACGCGTGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATCTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCTCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGCTGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATCCTTCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGAAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATTATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

85.854

100

0.859
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561

Multiple sequence alignment