Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   MMH06_RS00645 Genome accession   NZ_OV904788
Coordinates   130279..130968 (-) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain RMV7 isolate RMV7domi     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 125279..135968
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MMH06_RS00620 - 125965..126323 (+) 359 Protein_123 lanthionine synthetase LanC family protein -
  MMH06_RS00625 (IONPJBJN_00120) - 126223..126693 (+) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  MMH06_RS00630 (IONPJBJN_00121) - 126852..128084 (+) 1233 WP_000765684.1 MFS transporter -
  MMH06_RS00635 (IONPJBJN_00122) cbpJ 128202..129200 (-) 999 WP_000771129.1 choline-binding protein CbpJ -
  MMH06_RS00640 (IONPJBJN_00123) cbpC 129219..130181 (-) 963 WP_000698035.1 choline-binding protein CbpC -
  MMH06_RS00645 (IONPJBJN_00124) covR 130279..130968 (-) 690 WP_000518011.1 response regulator transcription factor Regulator
  MMH06_RS00650 (IONPJBJN_00125) gndA 130980..132404 (-) 1425 WP_000158792.1 NADP-dependent phosphogluconate dehydrogenase -
  MMH06_RS00655 (IONPJBJN_00126) mapZ 132480..133874 (-) 1395 WP_000039290.1 mid-cell-anchored protein MapZ -
  MMH06_RS00660 (IONPJBJN_00127) - 133887..135044 (-) 1158 WP_000711398.1 class I SAM-dependent RNA methyltransferase -
  MMH06_RS00670 (IONPJBJN_00128) gpsB 135530..135871 (-) 342 WP_000200644.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=1152061 MMH06_RS00645 WP_000518011.1 130279..130968(-) (covR) [Streptococcus pneumoniae strain RMV7 isolate RMV7domi]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1152061 MMH06_RS00645 WP_000518011.1 130279..130968(-) (covR) [Streptococcus pneumoniae strain RMV7 isolate RMV7domi]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment