Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   MD993_RS02450 Genome accession   NZ_OV648025
Coordinates   533539..534096 (+) Length   185 a.a.
NCBI ID   WP_369821465.1    Uniprot ID   -
Organism   Staphylococcus argenteus isolate 20S00001-1_long     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 528539..539096
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MD993_RS02425 cysE 529740..530387 (+) 648 WP_072291959.1 serine O-acetyltransferase -
  MD993_RS02430 cysS 530371..531771 (+) 1401 WP_031787937.1 cysteine--tRNA ligase -
  MD993_RS02435 - 531764..532168 (+) 405 WP_031787938.1 Mini-ribonuclease 3 -
  MD993_RS02440 rlmB 532176..532922 (+) 747 WP_000390335.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  MD993_RS02445 - 532922..533446 (+) 525 WP_000664733.1 NYN domain-containing protein -
  MD993_RS02450 sigH 533539..534096 (+) 558 WP_369821465.1 sigma-70 family RNA polymerase sigma factor Regulator
  MD993_RS02455 rpmG 534212..534355 (+) 144 WP_014373786.1 50S ribosomal protein L33 -
  MD993_RS02460 secE 534411..534593 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  MD993_RS02465 nusG 534606..535154 (+) 549 WP_001288299.1 transcription termination/antitermination protein NusG -
  MD993_RS02470 rplK 535335..535757 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  MD993_RS02475 rplA 535965..536657 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  MD993_RS02480 rplJ 536929..537429 (+) 501 WP_001273087.1 50S ribosomal protein L10 -
  MD993_RS02485 rplL 537473..537841 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  MD993_RS02490 - 538029..538637 (+) 609 WP_031787940.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 185 a.a.        Molecular weight: 22544.44 Da        Isoelectric Point: 9.6758

>NTDB_id=1151881 MD993_RS02450 WP_369821465.1 533539..534096(+) (sigH) [Staphylococcus argenteus isolate 20S00001-1_long]
MSVHNNVKKHSNIVDENEFEKLITDLKPLIIRRMKRFGFKYHDLEDLYQEILIKIYRATKTFDFKGEQPFVNYVQCLITS
VKYDYLRKCLASSRRMDSLVNEYKVIYPCALKYHDIERNYLNKLNVRELICQFKYLSAFEKEVMYFICDQYKPREIAQLM
NVKEKTIYNAIQRCKSKIRQHFKMF

Nucleotide


Download         Length: 558 bp        

>NTDB_id=1151881 MD993_RS02450 WP_369821465.1 533539..534096(+) (sigH) [Staphylococcus argenteus isolate 20S00001-1_long]
ATATCAGTGCATAATAATGTTAAAAAACACAGCAATATAGTTGACGAGAATGAATTTGAAAAGTTAATAACAGATTTGAA
ACCATTAATCATTCGACGTATGAAAAGGTTTGGTTTTAAATACCATGATTTGGAAGATTTATATCAAGAGATACTAATAA
AGATATATAGGGCAACTAAAACATTCGATTTTAAAGGTGAGCAACCATTCGTGAATTATGTTCAATGTTTAATCACTTCA
GTTAAATACGATTACCTAAGGAAGTGTTTAGCATCTTCTAGAAGAATGGATAGTTTAGTAAATGAATATAAAGTTATATA
TCCTTGTGCATTAAAGTATCATGACATTGAAAGAAACTATTTAAATAAACTGAATGTCAGAGAGTTGATTTGTCAATTTA
AATATTTAAGTGCATTTGAAAAAGAAGTAATGTATTTTATATGCGACCAATATAAACCAAGAGAGATTGCCCAATTGATG
AATGTTAAAGAAAAAACTATTTATAATGCAATTCAACGGTGTAAAAGTAAAATAAGACAGCATTTTAAAATGTTTTAA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(22-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

69.022

99.459

0.686
  sigH Staphylococcus aureus MW2

67.935

99.459

0.676

Multiple sequence alignment