Detailed information    

insolico Bioinformatically predicted

Overview

Name   hapR   Type   Regulator
Locus tag   HUW69_RS11285 Genome accession   NZ_LT992490
Coordinates   2538895..2539506 (+) Length   203 a.a.
NCBI ID   WP_000340100.1    Uniprot ID   Q4F6W7
Organism   Vibrio cholerae strain 4295STDY6534200     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2533895..2544506
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HUW69_RS11265 (SAMEA4374365_02295) - 2534236..2535153 (-) 918 WP_000271069.1 ABC transporter ATP-binding protein -
  HUW69_RS11270 (SAMEA4374365_02296) - 2535528..2537174 (-) 1647 WP_000484913.1 SulP family inorganic anion transporter -
  HUW69_RS11275 (SAMEA4374365_02297) can 2537322..2537990 (+) 669 WP_001114112.1 carbonate dehydratase -
  HUW69_RS11280 (SAMEA4374365_02298) hpt 2538066..2538599 (-) 534 WP_000683351.1 hypoxanthine phosphoribosyltransferase -
  HUW69_RS11285 (SAMEA4374365_02299) hapR 2538895..2539506 (+) 612 WP_000340100.1 quorum-sensing master transcriptional regulator HapR Regulator
  HUW69_RS11290 (SAMEA4374365_02300) rsmI 2539716..2540582 (-) 867 WP_000131551.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  HUW69_RS11295 (SAMEA4374365_02301) - 2540652..2542457 (+) 1806 WP_001015483.1 penicillin-binding protein activator -
  HUW69_RS11300 (SAMEA4374365_02302) - 2542444..2542812 (+) 369 WP_032471957.1 YraN family protein -
  HUW69_RS11305 (SAMEA4374365_02303) - 2542816..2543406 (+) 591 WP_000887295.1 phosphoheptose isomerase -
  HUW69_RS11310 (SAMEA4374365_02304) - 2543409..2543978 (+) 570 WP_000789633.1 BON domain-containing protein -

Sequence

Protein


Download         Length: 203 a.a.        Molecular weight: 23720.44 Da        Isoelectric Point: 6.6356

>NTDB_id=1150280 HUW69_RS11285 WP_000340100.1 2538895..2539506(+) (hapR) [Vibrio cholerae strain 4295STDY6534200]
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLVDSYLNMLCIYKN

Nucleotide


Download         Length: 612 bp        

>NTDB_id=1150280 HUW69_RS11285 WP_000340100.1 2538895..2539506(+) (hapR) [Vibrio cholerae strain 4295STDY6534200]
ATGGACGCATCAATCGAAAAACGCCCTCGAACTCGGCTGTCGCCTCAAAAACGTAAACTACAACTGATGGAAATCGCATT
GGAAGTATTTGCTAAACGTGGCATTGGTCGCGGTGGTCACGCTGATATTGCCGAGATTGCGCAAGTCTCCGTAGCAACCG
TGTTCAACTACTTCCCAACTCGCGAAGATCTCGTTGACGATGTGCTGAATTTTGTGGTTCGTCAGTACTCCAACTTCTTG
ACCGATCACATCGATCTTGATTTGGATGTGAAAACCAACCTACAAACCCTGTGCAAAGAGATGGTGAAATTGGCGATGAC
TGATTGTCACTGGCTCAAAGTCTGGTTTGAGTGGAGTGCTTCAACCCGTGACGAAGTTTGGCCACTGTTTGTATCCACCA
ACCGTACGAACCAACTGCTGATCAGAAATATGTTTATGAAAGCGATGGAGCGTGGCGAATTGTGTGAGAAACACGATGTC
GACAACATGGCTAGCCTATTCCACGGCATCTTCTACTCCATCTTCTTACAAGTGAACCGTTTAGGTGAACAAGAAGCGGT
GTATAAGCTGGTCGATAGCTACCTCAATATGCTGTGTATCTATAAGAACTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, tetR family (TetR_N)

(23-67)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4F6W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hapR Vibrio cholerae C6706

99.507

100

0.995
  hapR Vibrio cholerae strain A1552

99.507

100

0.995
  opaR Vibrio parahaemolyticus RIMD 2210633

72.727

97.537

0.709

Multiple sequence alignment