Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   DXE38_RS00140 Genome accession   NZ_LT992477
Coordinates   18624..19310 (+) Length   228 a.a.
NCBI ID   WP_001825349.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 22_LA_562     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 549..23100 18624..19310 within 0


Gene organization within MGE regions


Location: 549..23100
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE38_RS00015 - 1932..2222 (+) 291 WP_000179858.1 hypothetical protein -
  DXE38_RS00020 - 2238..4148 (+) 1911 WP_000429558.1 minor structural protein -
  DXE38_RS00025 - 4148..5614 (+) 1467 WP_031775920.1 BppU family phage baseplate upper protein -
  DXE38_RS00030 - 5614..6003 (+) 390 WP_001166599.1 DUF2977 domain-containing protein -
  DXE38_RS00035 - 5996..6160 (+) 165 WP_000916020.1 XkdX family protein -
  DXE38_RS00040 - 6206..6505 (+) 300 WP_000466775.1 DUF2951 family protein -
  DXE38_RS00045 - 6641..6943 (+) 303 WP_000339142.1 phage holin -
  DXE38_RS00050 - 6955..8409 (+) 1455 WP_000930261.1 N-acetylmuramoyl-L-alanine amidase -
  DXE38_RS00065 - 9104..9283 (+) 180 WP_000201920.1 hypothetical protein -
  DXE38_RS00070 - 9305..9832 (+) 528 WP_000455172.1 Panacea domain-containing protein -
  DXE38_RS00075 - 9822..10220 (+) 399 WP_000557464.1 hypothetical protein -
  DXE38_RS00080 - 10455..10964 (+) 510 Protein_13 Fic family protein -
  DXE38_RS00085 sel26 11379..12131 (+) 753 WP_001807829.1 staphylococcal enterotoxin type 26 -
  DXE38_RS00090 - 12334..12603 (-) 270 WP_000829750.1 hypothetical protein -
  DXE38_RS00095 mtnN 12917..13603 (+) 687 WP_000579272.1 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase -
  DXE38_RS00100 - 13623..14150 (+) 528 WP_000524902.1 YqeG family HAD IIIA-type phosphatase -
  DXE38_RS00105 yqeH 14151..15251 (+) 1101 WP_001280151.1 ribosome biogenesis GTPase YqeH -
  DXE38_RS00110 aroE 15265..16071 (+) 807 WP_000666746.1 shikimate dehydrogenase -
  DXE38_RS00115 yhbY 16075..16365 (+) 291 WP_000955234.1 ribosome assembly RNA-binding protein YhbY -
  DXE38_RS00120 nadD 16368..16937 (+) 570 WP_000725164.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  DXE38_RS00125 yqeK 16927..17511 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  DXE38_RS00130 rsfS 17512..17865 (+) 354 WP_001088020.1 ribosome silencing factor -
  DXE38_RS00135 - 17868..18584 (+) 717 WP_000084838.1 class I SAM-dependent DNA methyltransferase -
  DXE38_RS00140 comEA 18624..19310 (+) 687 WP_001825349.1 ComEA family DNA-binding protein Machinery gene
  DXE38_RS00145 - 19402..19863 (+) 462 WP_000439690.1 ComE operon protein 2 -
  DXE38_RS00150 comEC 19868..22069 (+) 2202 WP_001807826.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DXE38_RS00155 holA 22126..23100 (+) 975 WP_001282570.1 DNA polymerase III subunit delta -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25783.41 Da        Isoelectric Point: 9.3305

>NTDB_id=1150109 DXE38_RS00140 WP_001825349.1 18624..19310(+) (comEA) [Staphylococcus aureus isolate 22_LA_562]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTALKQSTSENSSLSKLEDVQVKDGDDSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1150109 DXE38_RS00140 WP_001825349.1 18624..19310(+) (comEA) [Staphylococcus aureus isolate 22_LA_562]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATGATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

96.476

99.561

0.961
  comEA Staphylococcus aureus N315

96.476

99.561

0.961

Multiple sequence alignment