Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DXE57_RS12885 Genome accession   NZ_LT992476
Coordinates   2486180..2486749 (-) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus isolate 21_LA_436     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2481180..2491749
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE57_RS12840 - 2481654..2482262 (-) 609 WP_000020293.1 class I SAM-dependent methyltransferase -
  DXE57_RS12845 rplL 2482437..2482805 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DXE57_RS12850 rplJ 2482848..2483348 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  DXE57_RS12860 rplA 2483620..2484312 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  DXE57_RS12865 rplK 2484520..2484942 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  DXE57_RS12870 nusG 2485123..2485671 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DXE57_RS12875 secE 2485684..2485866 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DXE57_RS12880 rpmG 2485922..2486065 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  DXE57_RS12885 sigH 2486180..2486749 (-) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  DXE57_RS12890 - 2486831..2487355 (-) 525 WP_000664738.1 NYN domain-containing protein -
  DXE57_RS12895 rlmB 2487355..2488101 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DXE57_RS12900 - 2488109..2488513 (-) 405 WP_000370181.1 Mini-ribonuclease 3 -
  DXE57_RS12905 cysS 2488506..2489906 (-) 1401 WP_000631961.1 cysteine--tRNA ligase -
  DXE57_RS12910 cysE 2489890..2490537 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=1150105 DXE57_RS12885 WP_000872879.1 2486180..2486749(-) (sigH) [Staphylococcus aureus isolate 21_LA_436]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1150105 DXE57_RS12885 WP_000872879.1 2486180..2486749(-) (sigH) [Staphylococcus aureus isolate 21_LA_436]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment