Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DXE41_RS09815 Genome accession   NZ_LT992475
Coordinates   1849929..1850498 (-) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus isolate 20_LA_415     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1844929..1855498
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE41_RS09770 - 1845403..1846011 (-) 609 WP_000020293.1 class I SAM-dependent methyltransferase -
  DXE41_RS09775 rplL 1846186..1846554 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DXE41_RS09780 rplJ 1846597..1847097 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  DXE41_RS09790 rplA 1847369..1848061 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  DXE41_RS09795 rplK 1848269..1848691 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  DXE41_RS09800 nusG 1848872..1849420 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DXE41_RS09805 secE 1849433..1849615 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DXE41_RS09810 rpmG 1849671..1849814 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  DXE41_RS09815 sigH 1849929..1850498 (-) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  DXE41_RS09820 - 1850580..1851104 (-) 525 WP_000664738.1 NYN domain-containing protein -
  DXE41_RS09825 rlmB 1851104..1851850 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DXE41_RS09830 - 1851858..1852262 (-) 405 WP_000370181.1 Mini-ribonuclease 3 -
  DXE41_RS09835 cysS 1852255..1853655 (-) 1401 WP_000631961.1 cysteine--tRNA ligase -
  DXE41_RS09840 cysE 1853639..1854286 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=1150056 DXE41_RS09815 WP_000872879.1 1849929..1850498(-) (sigH) [Staphylococcus aureus isolate 20_LA_415]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1150056 DXE41_RS09815 WP_000872879.1 1849929..1850498(-) (sigH) [Staphylococcus aureus isolate 20_LA_415]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment