Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   DXE66_RS11430 Genome accession   NZ_LT992474
Coordinates   2268782..2269468 (-) Length   228 a.a.
NCBI ID   WP_001825349.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 19_LA_388     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2263782..2274468
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE66_RS11410 rpsT 2264696..2264947 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  DXE66_RS11415 holA 2264992..2265966 (-) 975 WP_001282570.1 DNA polymerase III subunit delta -
  DXE66_RS11420 comEC 2266023..2268224 (-) 2202 WP_001807826.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DXE66_RS11425 - 2268229..2268690 (-) 462 WP_000439690.1 ComE operon protein 2 -
  DXE66_RS11430 comEA 2268782..2269468 (-) 687 WP_001825349.1 ComEA family DNA-binding protein Machinery gene
  DXE66_RS11435 - 2269508..2270224 (-) 717 WP_000084838.1 class I SAM-dependent DNA methyltransferase -
  DXE66_RS11440 rsfS 2270227..2270580 (-) 354 WP_001088020.1 ribosome silencing factor -
  DXE66_RS11445 yqeK 2270581..2271165 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  DXE66_RS11450 nadD 2271155..2271724 (-) 570 WP_000725164.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  DXE66_RS11455 yhbY 2271727..2272017 (-) 291 WP_000955234.1 ribosome assembly RNA-binding protein YhbY -
  DXE66_RS11460 aroE 2272021..2272827 (-) 807 WP_000666746.1 shikimate dehydrogenase -
  DXE66_RS11465 yqeH 2272841..2273941 (-) 1101 WP_001280151.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25783.41 Da        Isoelectric Point: 9.3305

>NTDB_id=1150004 DXE66_RS11430 WP_001825349.1 2268782..2269468(-) (comEA) [Staphylococcus aureus isolate 19_LA_388]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTALKQSTSENSSLSKLEDVQVKDGDDSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1150004 DXE66_RS11430 WP_001825349.1 2268782..2269468(-) (comEA) [Staphylococcus aureus isolate 19_LA_388]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATGATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

96.476

99.561

0.961
  comEA Staphylococcus aureus N315

96.476

99.561

0.961

Multiple sequence alignment