Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DXE66_RS06170 Genome accession   NZ_LT992474
Coordinates   1209632..1210201 (+) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus isolate 19_LA_388     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1204632..1215201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE66_RS06145 cysE 1205844..1206491 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  DXE66_RS06150 cysS 1206475..1207875 (+) 1401 WP_000631961.1 cysteine--tRNA ligase -
  DXE66_RS06155 - 1207868..1208272 (+) 405 WP_000370181.1 Mini-ribonuclease 3 -
  DXE66_RS06160 rlmB 1208280..1209026 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DXE66_RS06165 - 1209026..1209550 (+) 525 WP_000664738.1 NYN domain-containing protein -
  DXE66_RS06170 sigH 1209632..1210201 (+) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  DXE66_RS06175 rpmG 1210316..1210459 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  DXE66_RS06180 secE 1210515..1210697 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DXE66_RS06185 nusG 1210710..1211258 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DXE66_RS06190 rplK 1211439..1211861 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  DXE66_RS06195 rplA 1212069..1212761 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  DXE66_RS06205 rplJ 1213033..1213533 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  DXE66_RS06210 rplL 1213576..1213944 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DXE66_RS06215 - 1214119..1214727 (+) 609 WP_000020293.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=1149982 DXE66_RS06170 WP_000872879.1 1209632..1210201(+) (sigH) [Staphylococcus aureus isolate 19_LA_388]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1149982 DXE66_RS06170 WP_000872879.1 1209632..1210201(+) (sigH) [Staphylococcus aureus isolate 19_LA_388]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment