Detailed information    

insolico Bioinformatically predicted

Overview

Name   braS   Type   Regulator
Locus tag   DXE48_RS10035 Genome accession   NZ_LT992473
Coordinates   2022463..2023350 (+) Length   295 a.a.
NCBI ID   WP_000143420.1    Uniprot ID   A0A2S6DP21
Organism   Staphylococcus aureus isolate 14_5418     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2017463..2028350
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE48_RS10005 - 2018196..2018957 (+) 762 WP_031795534.1 alpha/beta hydrolase -
  DXE48_RS10010 - 2019201..2019656 (+) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  DXE48_RS15100 - 2019778..2019879 (+) 102 WP_000731972.1 SE2200 family small protein -
  DXE48_RS10020 - 2019939..2021363 (-) 1425 WP_031795533.1 alkaline phosphatase -
  DXE48_RS10025 - 2021561..2021761 (+) 201 WP_000604731.1 hypothetical protein -
  DXE48_RS10030 braR 2021787..2022452 (+) 666 WP_000697873.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  DXE48_RS10035 braS 2022463..2023350 (+) 888 WP_000143420.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  DXE48_RS10040 - 2023458..2024213 (+) 756 WP_000923768.1 ABC transporter ATP-binding protein -
  DXE48_RS10045 - 2024210..2026210 (+) 2001 WP_031795532.1 ABC transporter permease -
  DXE48_RS10050 - 2026879..2026992 (+) 114 WP_014937089.1 hypothetical protein -
  DXE48_RS10060 - 2027374..2027634 (+) 261 WP_014937088.1 hypothetical protein -
  DXE48_RS10065 - 2027644..2028141 (+) 498 WP_001065267.1 glutathione peroxidase -
  DXE48_RS10070 - 2028249..2028341 (-) 93 WP_031774855.1 hypothetical protein -

Sequence

Protein


Download         Length: 295 a.a.        Molecular weight: 34045.32 Da        Isoelectric Point: 5.8962

>NTDB_id=1149966 DXE48_RS10035 WP_000143420.1 2022463..2023350(+) (braS) [Staphylococcus aureus isolate 14_5418]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide


Download         Length: 888 bp        

>NTDB_id=1149966 DXE48_RS10035 WP_000143420.1 2022463..2023350(+) (braS) [Staphylococcus aureus isolate 14_5418]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(191-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DP21

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braS Staphylococcus aureus N315

99.322

100

0.993

Multiple sequence alignment