Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   DXE48_RS10030 Genome accession   NZ_LT992473
Coordinates   2021787..2022452 (+) Length   221 a.a.
NCBI ID   WP_000697873.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 14_5418     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2016787..2027452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE48_RS10005 - 2018196..2018957 (+) 762 WP_031795534.1 alpha/beta hydrolase -
  DXE48_RS10010 - 2019201..2019656 (+) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  DXE48_RS15100 - 2019778..2019879 (+) 102 WP_000731972.1 SE2200 family small protein -
  DXE48_RS10020 - 2019939..2021363 (-) 1425 WP_031795533.1 alkaline phosphatase -
  DXE48_RS10025 - 2021561..2021761 (+) 201 WP_000604731.1 hypothetical protein -
  DXE48_RS10030 braR 2021787..2022452 (+) 666 WP_000697873.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  DXE48_RS10035 braS 2022463..2023350 (+) 888 WP_000143420.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  DXE48_RS10040 - 2023458..2024213 (+) 756 WP_000923768.1 ABC transporter ATP-binding protein -
  DXE48_RS10045 - 2024210..2026210 (+) 2001 WP_031795532.1 ABC transporter permease -
  DXE48_RS10050 - 2026879..2026992 (+) 114 WP_014937089.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25434.46 Da        Isoelectric Point: 4.6079

>NTDB_id=1149965 DXE48_RS10030 WP_000697873.1 2021787..2022452(+) (braR) [Staphylococcus aureus isolate 14_5418]
MKILIVEDDFVIAESLASELEKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=1149965 DXE48_RS10030 WP_000697873.1 2021787..2022452(+) (braR) [Staphylococcus aureus isolate 14_5418]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTGAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAGCCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCGATGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACTCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.095

100

0.991

Multiple sequence alignment