Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DXE48_RS06430 Genome accession   NZ_LT992473
Coordinates   1294446..1295015 (-) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus isolate 14_5418     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1289446..1300015
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE48_RS06385 - 1289920..1290528 (-) 609 WP_000020293.1 class I SAM-dependent methyltransferase -
  DXE48_RS06390 rplL 1290703..1291071 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DXE48_RS06395 rplJ 1291114..1291614 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  DXE48_RS06405 rplA 1291886..1292578 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  DXE48_RS06410 rplK 1292786..1293208 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  DXE48_RS06415 nusG 1293389..1293937 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DXE48_RS06420 secE 1293950..1294132 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DXE48_RS06425 rpmG 1294188..1294331 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  DXE48_RS06430 sigH 1294446..1295015 (-) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  DXE48_RS06435 - 1295097..1295621 (-) 525 WP_000664738.1 NYN domain-containing protein -
  DXE48_RS06440 rlmB 1295621..1296367 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DXE48_RS06445 - 1296375..1296779 (-) 405 WP_000370181.1 Mini-ribonuclease 3 -
  DXE48_RS06450 cysS 1296772..1298172 (-) 1401 WP_000631961.1 cysteine--tRNA ligase -
  DXE48_RS06455 cysE 1298156..1298803 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=1149959 DXE48_RS06430 WP_000872879.1 1294446..1295015(-) (sigH) [Staphylococcus aureus isolate 14_5418]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1149959 DXE48_RS06430 WP_000872879.1 1294446..1295015(-) (sigH) [Staphylococcus aureus isolate 14_5418]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment