Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   DXE26_RS13445 Genome accession   NZ_LT992472
Coordinates   2621176..2621862 (-) Length   228 a.a.
NCBI ID   WP_001825349.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 10_5235     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2616176..2626862
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE26_RS13425 rpsT 2617090..2617341 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  DXE26_RS13430 holA 2617386..2618360 (-) 975 WP_001282570.1 DNA polymerase III subunit delta -
  DXE26_RS13435 comEC 2618417..2620618 (-) 2202 WP_001807826.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DXE26_RS13440 - 2620623..2621084 (-) 462 WP_000439690.1 ComE operon protein 2 -
  DXE26_RS13445 comEA 2621176..2621862 (-) 687 WP_001825349.1 ComEA family DNA-binding protein Machinery gene
  DXE26_RS13450 - 2621902..2622618 (-) 717 WP_000084838.1 class I SAM-dependent DNA methyltransferase -
  DXE26_RS13455 rsfS 2622621..2622974 (-) 354 WP_001088020.1 ribosome silencing factor -
  DXE26_RS13460 yqeK 2622975..2623559 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  DXE26_RS13465 nadD 2623549..2624118 (-) 570 WP_000725164.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  DXE26_RS13470 yhbY 2624121..2624411 (-) 291 WP_000955234.1 ribosome assembly RNA-binding protein YhbY -
  DXE26_RS13475 aroE 2624415..2625221 (-) 807 WP_000666746.1 shikimate dehydrogenase -
  DXE26_RS13480 yqeH 2625235..2626335 (-) 1101 WP_001280151.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25783.41 Da        Isoelectric Point: 9.3305

>NTDB_id=1149925 DXE26_RS13445 WP_001825349.1 2621176..2621862(-) (comEA) [Staphylococcus aureus isolate 10_5235]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTALKQSTSENSSLSKLEDVQVKDGDDSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1149925 DXE26_RS13445 WP_001825349.1 2621176..2621862(-) (comEA) [Staphylococcus aureus isolate 10_5235]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATGATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

96.476

99.561

0.961
  comEA Staphylococcus aureus N315

96.476

99.561

0.961

Multiple sequence alignment