Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   DXE26_RS10290 Genome accession   NZ_LT992472
Coordinates   1972513..1973436 (+) Length   307 a.a.
NCBI ID   WP_114666348.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 10_5235     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1925176..1974344 1972513..1973436 within 0
IS/Tn 1973397..1974344 1972513..1973436 flank -39


Gene organization within MGE regions


Location: 1925176..1974344
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE26_RS10045 - 1925176..1926393 (-) 1218 WP_001291561.1 tyrosine-type recombinase/integrase -
  DXE26_RS10050 - 1926475..1926678 (-) 204 WP_000814511.1 excisionase -
  DXE26_RS14550 - 1926662..1926913 (+) 252 WP_001845478.1 hypothetical protein -
  DXE26_RS10060 - 1927139..1927369 (-) 231 WP_000857133.1 helix-turn-helix domain-containing protein -
  DXE26_RS10065 - 1927366..1927788 (-) 423 WP_000804885.1 sigma-70 family RNA polymerase sigma factor -
  DXE26_RS10075 - 1928293..1928646 (+) 354 WP_001227347.1 helix-turn-helix transcriptional regulator -
  DXE26_RS10080 - 1928706..1928873 (-) 168 WP_000336323.1 cysteine-rich KTR domain-containing protein -
  DXE26_RS10085 tet(M) 1928992..1930911 (-) 1920 WP_000691736.1 tetracycline resistance ribosomal protection protein Tet(M) -
  DXE26_RS10090 - 1930927..1931043 (-) 117 WP_001814923.1 tetracycline resistance determinant leader peptide -
  DXE26_RS10095 - 1931288..1932220 (-) 933 WP_001224318.1 conjugal transfer protein -
  DXE26_RS10100 - 1932217..1933218 (-) 1002 WP_000769868.1 lysozyme family protein -
  DXE26_RS10105 - 1933215..1935392 (-) 2178 WP_000804748.1 CD3337/EF1877 family mobilome membrane protein -
  DXE26_RS10110 - 1935395..1937842 (-) 2448 WP_000331163.1 ATP-binding protein -
  DXE26_RS10115 - 1937826..1938218 (-) 393 WP_000723888.1 conjugal transfer protein -
  DXE26_RS10120 - 1938307..1938804 (-) 498 WP_000342539.1 antirestriction protein ArdA -
  DXE26_RS10125 - 1938921..1939142 (-) 222 WP_001009056.1 hypothetical protein -
  DXE26_RS10130 mobT 1939185..1940390 (-) 1206 WP_000398286.1 MobT family relaxase -
  DXE26_RS10135 - 1940413..1940565 (-) 153 WP_000879507.1 hypothetical protein -
  DXE26_RS10140 - 1940568..1941953 (-) 1386 WP_000813488.1 FtsK/SpoIIIE domain-containing protein -
  DXE26_RS10145 - 1941982..1942368 (-) 387 WP_000985015.1 YdcP family protein -
  DXE26_RS10150 - 1942384..1942698 (-) 315 WP_000420682.1 YdcP family protein -
  DXE26_RS10160 - 1943067..1943860 (-) 794 Protein_1882 transposase -
  DXE26_RS10165 - 1944269..1945585 (-) 1317 WP_001124512.1 CoA-disulfide reductase -
  DXE26_RS10170 - 1945637..1946461 (-) 825 WP_001182436.1 Cof-type HAD-IIB family hydrolase -
  DXE26_RS10175 - 1946575..1946883 (+) 309 WP_000390575.1 metal-sulfur cluster assembly factor -
  DXE26_RS10180 - 1947481..1949295 (+) 1815 WP_001044238.1 acyltransferase family protein -
  DXE26_RS10185 clpB 1949498..1952107 (+) 2610 WP_000353948.1 ATP-dependent chaperone ClpB -
  DXE26_RS10190 - 1952166..1953035 (-) 870 WP_001047061.1 LysR family transcriptional regulator -
  DXE26_RS10195 - 1953166..1953681 (+) 516 WP_000700886.1 YbhB/YbcL family Raf kinase inhibitor-like protein -
  DXE26_RS10200 - 1953992..1954426 (+) 435 WP_000769695.1 MAP domain-containing protein -
  DXE26_RS10205 - 1954683..1954868 (-) 186 WP_000682089.1 YjzD family protein -
  DXE26_RS10210 - 1955163..1956104 (+) 942 WP_001100526.1 beta-ketoacyl-ACP synthase III -
  DXE26_RS10215 fabF 1956116..1957360 (+) 1245 WP_000081234.1 beta-ketoacyl-ACP synthase II -
  DXE26_RS10220 - 1957415..1957786 (-) 372 WP_000915159.1 DUF3899 domain-containing protein -
  DXE26_RS10225 opp3b 1958029..1958955 (+) 927 WP_000521531.1 oligopeptide ABC transporter permease -
  DXE26_RS10230 opp3C 1958955..1960025 (+) 1071 WP_000829637.1 oligopeptide ABC transporter permease -
  DXE26_RS10235 - 1960041..1961123 (+) 1083 WP_000140050.1 ABC transporter ATP-binding protein -
  DXE26_RS10240 - 1961113..1962054 (+) 942 WP_000786744.1 ABC transporter ATP-binding protein -
  DXE26_RS10245 - 1962073..1963728 (+) 1656 WP_000197091.1 peptide ABC transporter substrate-binding protein -
  DXE26_RS10250 opp3b 1963898..1964833 (+) 936 WP_001807927.1 oligopeptide ABC transporter permease -
  DXE26_RS10255 opp3C 1964823..1965842 (+) 1020 WP_000234063.1 oligopeptide ABC transporter permease -
  DXE26_RS10260 - 1965855..1966937 (+) 1083 WP_000976731.1 ABC transporter ATP-binding protein -
  DXE26_RS10265 - 1966927..1967853 (+) 927 WP_001064121.1 ABC transporter ATP-binding protein -
  DXE26_RS10270 - 1967881..1969503 (+) 1623 WP_000406183.1 peptide ABC transporter substrate-binding protein -
  DXE26_RS10275 trpS 1969623..1970612 (-) 990 WP_000448934.1 tryptophan--tRNA ligase -
  DXE26_RS10280 spxA 1970907..1971302 (+) 396 WP_000258003.1 transcriptional regulator SpxA -
  DXE26_RS10285 mecA 1971673..1972392 (+) 720 WP_001217731.1 adaptor protein MecA -
  DXE26_RS10290 coiA 1972513..1973436 (+) 924 WP_114666348.1 competence protein CoiA Machinery gene
  DXE26_RS10295 - 1973397..1974344 (-) 948 WP_000121214.1 IS30-like element ISSau1 family transposase -

Sequence

Protein


Download         Length: 307 a.a.        Molecular weight: 36374.46 Da        Isoelectric Point: 9.3782

>NTDB_id=1149910 DXE26_RS10290 WP_114666348.1 1972513..1973436(+) (coiA) [Staphylococcus aureus isolate 10_5235]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNESIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPISYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFQSMFINPITRKL
HTFNLEKKQIMMFQQIQYIGGHKYVAEKRNVKMSELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVHNYGYIFPEQIYIENHPIEWQLQVDLWLKNGESILVSDNLNYFKLLICQFKCNSSSHKTS

Nucleotide


Download         Length: 924 bp        

>NTDB_id=1149910 DXE26_RS10290 WP_114666348.1 1972513..1973436(+) (coiA) [Staphylococcus aureus isolate 10_5235]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGCGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCGGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAATCGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTTCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCAAAGTATGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATATAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGTCAAAATGAGTGAGTTGTTTAATGAGGCACCTTGTGATTATCATGCTGTTTATAAATTATCAAAATTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGCACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAGAAAGCATATTAGTAAGTGACAATCTTAATTATTTTAAACTGTTGA
TTTGTCAATTTAAGTGCAACAGTTCATCACATAAAACTTCATAA

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(6-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Staphylococcus aureus MW2

96.233

95.114

0.915
  coiA Staphylococcus aureus N315

95.89

95.114

0.912

Multiple sequence alignment