Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   DXE46_RS09040 Genome accession   NZ_LT992471
Coordinates   1776277..1776963 (-) Length   228 a.a.
NCBI ID   WP_001825349.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 17_LA_343     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1771277..1781963
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE46_RS09020 rpsT 1772191..1772442 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  DXE46_RS09025 holA 1772487..1773461 (-) 975 WP_001282570.1 DNA polymerase III subunit delta -
  DXE46_RS09030 comEC 1773518..1775719 (-) 2202 WP_001807826.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DXE46_RS09035 - 1775724..1776185 (-) 462 WP_000439690.1 ComE operon protein 2 -
  DXE46_RS09040 comEA 1776277..1776963 (-) 687 WP_001825349.1 ComEA family DNA-binding protein Machinery gene
  DXE46_RS09045 - 1777003..1777719 (-) 717 WP_000084838.1 class I SAM-dependent DNA methyltransferase -
  DXE46_RS09050 rsfS 1777722..1778075 (-) 354 WP_001088020.1 ribosome silencing factor -
  DXE46_RS09055 yqeK 1778076..1778660 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  DXE46_RS09060 nadD 1778650..1779219 (-) 570 WP_000725164.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  DXE46_RS09065 yhbY 1779222..1779512 (-) 291 WP_000955234.1 ribosome assembly RNA-binding protein YhbY -
  DXE46_RS09070 aroE 1779516..1780322 (-) 807 WP_000666746.1 shikimate dehydrogenase -
  DXE46_RS09075 yqeH 1780336..1781436 (-) 1101 WP_001280151.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25783.41 Da        Isoelectric Point: 9.3305

>NTDB_id=1149873 DXE46_RS09040 WP_001825349.1 1776277..1776963(-) (comEA) [Staphylococcus aureus isolate 17_LA_343]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTALKQSTSENSSLSKLEDVQVKDGDDSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1149873 DXE46_RS09040 WP_001825349.1 1776277..1776963(-) (comEA) [Staphylococcus aureus isolate 17_LA_343]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATGATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

96.476

99.561

0.961
  comEA Staphylococcus aureus N315

96.476

99.561

0.961

Multiple sequence alignment