Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DXE46_RS03360 Genome accession   NZ_LT992471
Coordinates   659556..660125 (+) Length   189 a.a.
NCBI ID   WP_000872866.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 17_LA_343     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 654556..665125
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE46_RS03335 cysE 655768..656415 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  DXE46_RS03340 cysS 656399..657799 (+) 1401 WP_000631961.1 cysteine--tRNA ligase -
  DXE46_RS03345 - 657792..658196 (+) 405 WP_000370181.1 Mini-ribonuclease 3 -
  DXE46_RS03350 rlmB 658204..658950 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DXE46_RS03355 - 658950..659474 (+) 525 WP_000664738.1 NYN domain-containing protein -
  DXE46_RS03360 sigH 659556..660125 (+) 570 WP_000872866.1 sigma-70 family RNA polymerase sigma factor Regulator
  DXE46_RS03365 rpmG 660240..660383 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  DXE46_RS03370 secE 660439..660621 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DXE46_RS03375 nusG 660634..661182 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DXE46_RS03380 rplK 661363..661785 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  DXE46_RS03385 rplA 661993..662685 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  DXE46_RS03395 rplJ 662957..663457 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  DXE46_RS03400 rplL 663500..663868 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DXE46_RS03405 - 664043..664651 (+) 609 WP_000020293.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23043.97 Da        Isoelectric Point: 9.6030

>NTDB_id=1149850 DXE46_RS03360 WP_000872866.1 659556..660125(+) (sigH) [Staphylococcus aureus isolate 17_LA_343]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRCIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1149850 DXE46_RS03360 WP_000872866.1 659556..660125(+) (sigH) [Staphylococcus aureus isolate 17_LA_343]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGATGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.413

100

0.984
  sigH Staphylococcus aureus N315

97.354

100

0.974

Multiple sequence alignment