Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   DXE46_RS00480 Genome accession   NZ_LT992471
Coordinates   96588..98225 (-) Length   545 a.a.
NCBI ID   WP_031912755.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 17_LA_343     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 89823..105203 96588..98225 within 0


Gene organization within MGE regions


Location: 89823..105203
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE46_RS00440 mecA 89823..91832 (-) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  DXE46_RS00445 - 91929..92915 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  DXE46_RS00450 - 92905..93147 (+) 243 Protein_81 type I restriction enzyme endonuclease domain-containing protein -
  DXE46_RS00455 - 93138..94748 (-) 1611 Protein_82 IS1182 family transposase -
  DXE46_RS00460 - 94797..95303 (-) 507 WP_001092189.1 DUF1643 domain-containing protein -
  DXE46_RS00465 - 95318..95629 (-) 312 WP_000700851.1 DUF960 family protein -
  DXE46_RS00475 - 95716..96066 (-) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  DXE46_RS00480 ccrB 96588..98225 (-) 1638 WP_031912755.1 cassette chromosome recombinase CcrB Machinery gene
  DXE46_RS00485 ccrA 98247..99596 (-) 1350 WP_000815652.1 cassette chromosome recombinase CcrA Machinery gene
  DXE46_RS00490 cch1 99830..101617 (-) 1788 WP_000122621.1 cassette chromosome replicative helicase -
  DXE46_RS00495 ssb 101617..101907 (-) 291 WP_001036437.1 cassette chromosome ssDNA-binding protein -
  DXE46_RS00500 - 102046..103095 (+) 1050 WP_000613248.1 hypothetical protein -
  DXE46_RS00505 - 103713..105203 (+) 1491 WP_000554504.1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 545 a.a.        Molecular weight: 62967.16 Da        Isoelectric Point: 9.9805

>NTDB_id=1149845 DXE46_RS00480 WP_031912755.1 96588..98225(-) (ccrB) [Staphylococcus aureus isolate 17_LA_343]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVM
IYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTTNT
LKDGTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVARVNQENKVDGAALHHDIAYKQQ
QYDEVQTKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKSLFDAKQISKLLQHIFQDIKHMEKS
RLKALYLSVIDRINIRKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI

Nucleotide


Download         Length: 1638 bp        

>NTDB_id=1149845 DXE46_RS00480 WP_031912755.1 96588..98225(-) (ccrB) [Staphylococcus aureus isolate 17_LA_343]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGATCGTGGTA
TTTCAGGTAAATCTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATAGATTGTGTTATG
ATCTACAAAACAAACCGATTAGCTCGTAATACATCGGATCTTCTGAAAATCGTCGAAGATTTGCATAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGGCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTACCACTAGGTTATGACAAAATACCAGATAGTAAACACGAGCTAATGATTAACCAACATGAAGCTAATATTGTAAAATA
TATATTCGAGTCCTATGCCAAAGGACATGGCTATCGTAAAATAGCCAATGCATTGAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTTCATGGTAAAGGAACGA
ATCTGCTTACAGGCATTATCCATTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACAACGAATACAACGAATACA
CTTAAAGATGGGACCAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGC
AAACAGTGTAAGAGCTGATGTGATTGAAGATTATGTAATGAAGCAAATACTCGAAATAGTCAAAAGTGATAAAGTCATTC
AACGCGTTGTAGCACGTGTTAATCAAGAAAATAAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAA
CAATATGATGAAGTACAAACCAAACTAAATAACTTGATTAAAACCATAGAGGATAATCCGGACTTAACATCAGTAATCAG
ACCAAGTATTCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAG
ATAAGTCTTTATTTGATGCCAAACAAATCAGTAAACTATTACAACACATCTTTCAAGATATTAAGCACATGGAAAAATCT
CGACTCAAAGCATTGTACCTATCAGTGATTGATCGTATTAATATTAGAAAAGATGGTAATCATAAAAAACAATTCTATGT
CACACTCAAACTTAATAACGAAATCATTAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGT
CTTTATTTTTGCCCCAAACACTATATCTTACTATTTAG

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(11-156)

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-359)

Recombinase (Recombinase)

(180-280)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

96.881

100

0.969

Multiple sequence alignment