Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DXE64_RS06090 Genome accession   NZ_LT992470
Coordinates   1198147..1198716 (-) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus isolate 13_LA_301     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1193147..1203716
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE64_RS06045 - 1193621..1194229 (-) 609 WP_000020293.1 class I SAM-dependent methyltransferase -
  DXE64_RS06050 rplL 1194404..1194772 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DXE64_RS06055 rplJ 1194815..1195315 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  DXE64_RS06065 rplA 1195587..1196279 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  DXE64_RS06070 rplK 1196487..1196909 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  DXE64_RS06075 nusG 1197090..1197638 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DXE64_RS06080 secE 1197651..1197833 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DXE64_RS06085 rpmG 1197889..1198032 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  DXE64_RS06090 sigH 1198147..1198716 (-) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  DXE64_RS06095 - 1198798..1199322 (-) 525 WP_000664738.1 NYN domain-containing protein -
  DXE64_RS06100 rlmB 1199322..1200068 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DXE64_RS06105 - 1200076..1200480 (-) 405 WP_000370181.1 Mini-ribonuclease 3 -
  DXE64_RS06110 cysS 1200473..1201873 (-) 1401 WP_000631961.1 cysteine--tRNA ligase -
  DXE64_RS06115 cysE 1201857..1202504 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=1149825 DXE64_RS06090 WP_000872879.1 1198147..1198716(-) (sigH) [Staphylococcus aureus isolate 13_LA_301]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1149825 DXE64_RS06090 WP_000872879.1 1198147..1198716(-) (sigH) [Staphylococcus aureus isolate 13_LA_301]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment