Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DXE47_RS10110 Genome accession   NZ_LT992468
Coordinates   1898308..1898877 (+) Length   189 a.a.
NCBI ID   WP_000872866.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 12_LA_293     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1893308..1903877
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE47_RS10085 cysE 1894520..1895167 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  DXE47_RS10090 cysS 1895151..1896551 (+) 1401 WP_000631961.1 cysteine--tRNA ligase -
  DXE47_RS10095 - 1896544..1896948 (+) 405 WP_000370181.1 Mini-ribonuclease 3 -
  DXE47_RS10100 rlmB 1896956..1897702 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DXE47_RS10105 - 1897702..1898226 (+) 525 WP_000664738.1 NYN domain-containing protein -
  DXE47_RS10110 sigH 1898308..1898877 (+) 570 WP_000872866.1 sigma-70 family RNA polymerase sigma factor Regulator
  DXE47_RS10115 rpmG 1898992..1899135 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  DXE47_RS10120 secE 1899191..1899373 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DXE47_RS10125 nusG 1899386..1899934 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DXE47_RS10130 rplK 1900115..1900537 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  DXE47_RS10135 rplA 1900745..1901437 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  DXE47_RS10145 rplJ 1901709..1902209 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  DXE47_RS10150 rplL 1902252..1902620 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DXE47_RS10155 - 1902795..1903403 (+) 609 WP_000020293.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23043.97 Da        Isoelectric Point: 9.6030

>NTDB_id=1149740 DXE47_RS10110 WP_000872866.1 1898308..1898877(+) (sigH) [Staphylococcus aureus isolate 12_LA_293]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRCIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1149740 DXE47_RS10110 WP_000872866.1 1898308..1898877(+) (sigH) [Staphylococcus aureus isolate 12_LA_293]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGATGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.413

100

0.984
  sigH Staphylococcus aureus N315

97.354

100

0.974

Multiple sequence alignment