Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   DXE59_RS12640 Genome accession   NZ_LT992467
Coordinates   2424257..2425243 (+) Length   328 a.a.
NCBI ID   WP_000959279.1    Uniprot ID   A0A2S6DCY7
Organism   Staphylococcus aureus isolate 16_LA_309     
Function   require for natural transformation (predicted from homology)   
Unclear

Genomic Context

Location: 2419257..2430243
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE59_RS12620 - 2419625..2421247 (+) 1623 WP_000406183.1 peptide ABC transporter substrate-binding protein -
  DXE59_RS12625 trpS 2421367..2422356 (-) 990 WP_000448934.1 tryptophan--tRNA ligase -
  DXE59_RS12630 spxA 2422651..2423046 (+) 396 WP_000258003.1 transcriptional regulator SpxA -
  DXE59_RS12635 mecA 2423417..2424136 (+) 720 WP_001217731.1 adaptor protein MecA -
  DXE59_RS12640 coiA 2424257..2425243 (+) 987 WP_000959279.1 competence protein CoiA Machinery gene
  DXE59_RS12645 pepF 2425291..2427099 (+) 1809 WP_000082727.1 oligoendopeptidase F -
  DXE59_RS12650 yjbH 2427559..2428365 (-) 807 WP_000896695.1 protease adaptor protein YjbH -
  DXE59_RS12655 - 2428388..2428753 (-) 366 WP_000214070.1 truncated hemoglobin YjbI -
  DXE59_RS12660 - 2428857..2429450 (-) 594 WP_000224612.1 CYTH domain-containing protein -
  DXE59_RS12665 - 2429636..2429983 (+) 348 WP_001242104.1 hypothetical protein -

Sequence

Protein


Download         Length: 328 a.a.        Molecular weight: 38800.32 Da        Isoelectric Point: 9.4277

>NTDB_id=1149705 DXE59_RS12640 WP_000959279.1 2424257..2425243(+) (coiA) [Staphylococcus aureus isolate 16_LA_309]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNESIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPISYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFQSMFINPITRKL
HTFNLEKKQIMMFQQIQYIGGHKYVAEKRNVKMSELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVHNYGYIFPEQIYIENHPIEWQLQVDLWLKNGESILVSDNLNYFKLKKFIVALESKTAIIEKLINNYLNISSDR
GNDVQILF

Nucleotide


Download         Length: 987 bp        

>NTDB_id=1149705 DXE59_RS12640 WP_000959279.1 2424257..2425243(+) (coiA) [Staphylococcus aureus isolate 16_LA_309]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGCGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCGGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAATCGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTTCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCAAAGTATGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATATAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGTCAAAATGAGTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAATTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGCACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAGAAAGCATATTAGTAAGTGACAATCTTAATTATTTTAAACTGAAAA
AGTTTATTGTTGCTCTAGAAAGTAAAACAGCGATTATAGAAAAACTTATTAACAATTATTTAAATATTAGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(6-308)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DCY7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Staphylococcus aureus N315

96.037

100

0.96
  coiA Staphylococcus aureus MW2

96.037

100

0.96

Multiple sequence alignment