Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DXE59_RS10135 Genome accession   NZ_LT992467
Coordinates   1964852..1965421 (+) Length   189 a.a.
NCBI ID   WP_000872866.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 16_LA_309     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1959852..1970421
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE59_RS10110 cysE 1961064..1961711 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  DXE59_RS10115 cysS 1961695..1963095 (+) 1401 WP_000631961.1 cysteine--tRNA ligase -
  DXE59_RS10120 - 1963088..1963492 (+) 405 WP_000370181.1 Mini-ribonuclease 3 -
  DXE59_RS10125 rlmB 1963500..1964246 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DXE59_RS10130 - 1964246..1964770 (+) 525 WP_000664738.1 NYN domain-containing protein -
  DXE59_RS10135 sigH 1964852..1965421 (+) 570 WP_000872866.1 sigma-70 family RNA polymerase sigma factor Regulator
  DXE59_RS10140 rpmG 1965536..1965679 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  DXE59_RS10145 secE 1965735..1965917 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DXE59_RS10150 nusG 1965930..1966478 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DXE59_RS10155 rplK 1966659..1967081 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  DXE59_RS10160 rplA 1967289..1967981 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  DXE59_RS10170 rplJ 1968253..1968753 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  DXE59_RS10175 rplL 1968796..1969164 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DXE59_RS10180 - 1969339..1969947 (+) 609 WP_000020293.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23043.97 Da        Isoelectric Point: 9.6030

>NTDB_id=1149697 DXE59_RS10135 WP_000872866.1 1964852..1965421(+) (sigH) [Staphylococcus aureus isolate 16_LA_309]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRCIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1149697 DXE59_RS10135 WP_000872866.1 1964852..1965421(+) (sigH) [Staphylococcus aureus isolate 16_LA_309]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGATGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.413

100

0.984
  sigH Staphylococcus aureus N315

97.354

100

0.974

Multiple sequence alignment