Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DXE30_RS12650 Genome accession   NZ_LT992466
Coordinates   2480525..2481094 (-) Length   189 a.a.
NCBI ID   WP_000872866.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 4_LA_208     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2475525..2486094
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE30_RS12605 - 2475999..2476607 (-) 609 WP_000020293.1 class I SAM-dependent methyltransferase -
  DXE30_RS12610 rplL 2476782..2477150 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DXE30_RS12615 rplJ 2477193..2477693 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  DXE30_RS12625 rplA 2477965..2478657 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  DXE30_RS12630 rplK 2478865..2479287 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  DXE30_RS12635 nusG 2479468..2480016 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DXE30_RS12640 secE 2480029..2480211 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DXE30_RS12645 rpmG 2480267..2480410 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  DXE30_RS12650 sigH 2480525..2481094 (-) 570 WP_000872866.1 sigma-70 family RNA polymerase sigma factor Regulator
  DXE30_RS12655 - 2481176..2481700 (-) 525 WP_000664738.1 NYN domain-containing protein -
  DXE30_RS12660 rlmB 2481700..2482446 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DXE30_RS12665 - 2482454..2482858 (-) 405 WP_000370181.1 Mini-ribonuclease 3 -
  DXE30_RS12670 cysS 2482851..2484251 (-) 1401 WP_000631961.1 cysteine--tRNA ligase -
  DXE30_RS12675 cysE 2484235..2484882 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23043.97 Da        Isoelectric Point: 9.6030

>NTDB_id=1149661 DXE30_RS12650 WP_000872866.1 2480525..2481094(-) (sigH) [Staphylococcus aureus isolate 4_LA_208]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRCIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1149661 DXE30_RS12650 WP_000872866.1 2480525..2481094(-) (sigH) [Staphylococcus aureus isolate 4_LA_208]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGATGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.413

100

0.984
  sigH Staphylococcus aureus N315

97.354

100

0.974

Multiple sequence alignment