Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DXE62_RS05965 Genome accession   NZ_LT992465
Coordinates   1167735..1168304 (-) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus isolate 6_LA_232     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1162735..1173304
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE62_RS05920 - 1163209..1163817 (-) 609 WP_000020293.1 class I SAM-dependent methyltransferase -
  DXE62_RS05925 rplL 1163992..1164360 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DXE62_RS05930 rplJ 1164403..1164903 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  DXE62_RS05940 rplA 1165175..1165867 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  DXE62_RS05945 rplK 1166075..1166497 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  DXE62_RS05950 nusG 1166678..1167226 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DXE62_RS05955 secE 1167239..1167421 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DXE62_RS05960 rpmG 1167477..1167620 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  DXE62_RS05965 sigH 1167735..1168304 (-) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  DXE62_RS05970 - 1168386..1168910 (-) 525 WP_000664738.1 NYN domain-containing protein -
  DXE62_RS05975 rlmB 1168910..1169656 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DXE62_RS05980 - 1169664..1170068 (-) 405 WP_000370181.1 Mini-ribonuclease 3 -
  DXE62_RS05985 cysS 1170061..1171461 (-) 1401 WP_000631961.1 cysteine--tRNA ligase -
  DXE62_RS05990 cysE 1171445..1172092 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=1149601 DXE62_RS05965 WP_000872879.1 1167735..1168304(-) (sigH) [Staphylococcus aureus isolate 6_LA_232]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1149601 DXE62_RS05965 WP_000872879.1 1167735..1168304(-) (sigH) [Staphylococcus aureus isolate 6_LA_232]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment