Detailed information
Bioinformatically predicted
Overview
| Name | comEA | Type | Machinery gene |
| Locus tag | DXE62_RS00695 | Genome accession | NZ_LT992465 |
| Coordinates | 108008..108694 (+) | Length | 228 a.a. |
| NCBI ID | WP_001825349.1 | Uniprot ID | - |
| Organism | Staphylococcus aureus isolate 6_LA_232 | ||
| Function | dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 53712..112484 | 108008..108694 | within | 0 |
Gene organization within MGE regions
Location: 53712..112484
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DXE62_RS00300 | - | 53712..54434 (+) | 723 | Protein_57 | Fic family protein | - |
| DXE62_RS00305 | - | 54530..55735 (-) | 1206 | WP_000264184.1 | tyrosine-type recombinase/integrase | - |
| DXE62_RS00310 | - | 55845..56459 (+) | 615 | WP_000191461.1 | hypothetical protein | - |
| DXE62_RS00315 | - | 56456..56602 (-) | 147 | WP_001013104.1 | hypothetical protein | - |
| DXE62_RS00320 | - | 56832..57416 (-) | 585 | WP_000825948.1 | hypothetical protein | - |
| DXE62_RS00325 | - | 57434..57895 (-) | 462 | WP_000525004.1 | hypothetical protein | - |
| DXE62_RS00330 | - | 57908..58231 (-) | 324 | WP_114637613.1 | helix-turn-helix domain-containing protein | - |
| DXE62_RS00335 | - | 58395..58643 (+) | 249 | WP_000272859.1 | helix-turn-helix domain-containing protein | - |
| DXE62_RS00340 | - | 58656..59099 (+) | 444 | WP_000435362.1 | hypothetical protein | - |
| DXE62_RS14715 | - | 59114..59263 (+) | 150 | WP_000771849.1 | hypothetical protein | - |
| DXE62_RS00345 | - | 59304..59516 (-) | 213 | WP_000362644.1 | hypothetical protein | - |
| DXE62_RS00350 | - | 59587..59730 (+) | 144 | WP_000939498.1 | hypothetical protein | - |
| DXE62_RS00355 | - | 59720..59929 (-) | 210 | WP_000642492.1 | hypothetical protein | - |
| DXE62_RS00360 | - | 59985..60230 (+) | 246 | WP_001025401.1 | DUF2829 domain-containing protein | - |
| DXE62_RS00365 | - | 60199..60564 (-) | 366 | WP_001128433.1 | hypothetical protein | - |
| DXE62_RS00370 | - | 60619..60835 (+) | 217 | Protein_72 | hypothetical protein | - |
| DXE62_RS00375 | - | 60862..61125 (+) | 264 | WP_001124195.1 | helix-turn-helix domain-containing protein | - |
| DXE62_RS00380 | - | 61137..61298 (+) | 162 | WP_001285949.1 | DUF1270 domain-containing protein | - |
| DXE62_RS00385 | - | 61377..61700 (+) | 324 | WP_000174994.1 | hypothetical protein | - |
| DXE62_RS00390 | - | 61715..62077 (+) | 363 | WP_031775157.1 | hypothetical protein | - |
| DXE62_RS00395 | - | 62074..63240 (+) | 1167 | WP_031795549.1 | DUF2800 domain-containing protein | - |
| DXE62_RS00400 | - | 63266..63823 (+) | 558 | WP_000645042.1 | DUF2815 family protein | - |
| DXE62_RS00405 | - | 63892..65844 (+) | 1953 | WP_078098872.1 | DNA polymerase | - |
| DXE62_RS00410 | - | 65857..66041 (+) | 185 | Protein_80 | DUF3113 family protein | - |
| DXE62_RS00415 | - | 66041..66442 (+) | 402 | WP_000113974.1 | SA1788 family PVL leukocidin-associated protein | - |
| DXE62_RS00420 | - | 66442..66696 (+) | 255 | WP_000022727.1 | DUF3310 domain-containing protein | - |
| DXE62_RS00425 | - | 66696..66944 (+) | 249 | WP_001802342.1 | SAV1978 family virulence-associated passenger protein | - |
| DXE62_RS00430 | - | 66958..67164 (+) | 207 | WP_000693989.1 | hypothetical protein | - |
| DXE62_RS00435 | - | 67167..67574 (+) | 408 | WP_000695771.1 | hypothetical protein | - |
| DXE62_RS00440 | - | 67571..67765 (+) | 195 | WP_000983950.1 | hypothetical protein | - |
| DXE62_RS00445 | - | 67762..68199 (+) | 438 | WP_000982714.1 | YopX family protein | - |
| DXE62_RS00450 | - | 68196..68561 (+) | 366 | WP_001105602.1 | hypothetical protein | - |
| DXE62_RS00455 | - | 68554..68802 (+) | 249 | WP_031795590.1 | DUF1024 family protein | - |
| DXE62_RS00460 | - | 68795..69331 (+) | 537 | WP_000185680.1 | dUTPase | - |
| DXE62_RS00465 | - | 69368..69574 (+) | 207 | WP_031795553.1 | DUF1381 domain-containing protein | - |
| DXE62_RS00470 | rinB | 69571..69723 (+) | 153 | WP_000595213.1 | transcriptional activator RinB | - |
| DXE62_RS00475 | - | 69791..69991 (+) | 201 | WP_031794940.1 | DUF1514 family protein | - |
| DXE62_RS00480 | - | 70043..72490 (+) | 2448 | WP_031795554.1 | virulence-associated E family protein | - |
| DXE62_RS00485 | - | 72593..72697 (-) | 105 | WP_011447017.1 | hypothetical protein | - |
| DXE62_RS00490 | - | 72831..73121 (+) | 291 | WP_000665203.1 | VRR-NUC domain-containing protein | - |
| DXE62_RS00495 | - | 73102..74469 (+) | 1368 | WP_078098871.1 | SNF2-related protein | - |
| DXE62_RS00500 | - | 74482..74919 (+) | 438 | WP_031795556.1 | transcriptional regulator | - |
| DXE62_RS00505 | - | 75076..75390 (+) | 315 | WP_031775147.1 | HNH endonuclease | - |
| DXE62_RS00510 | - | 75518..75823 (+) | 306 | WP_000778933.1 | P27 family phage terminase small subunit | - |
| DXE62_RS00515 | - | 75813..77504 (+) | 1692 | WP_000153538.1 | terminase large subunit | - |
| DXE62_RS00520 | - | 77509..78747 (+) | 1239 | WP_001100659.1 | phage portal protein | - |
| DXE62_RS00525 | - | 78731..79504 (+) | 774 | WP_000061862.1 | head maturation protease, ClpP-related | - |
| DXE62_RS00530 | - | 79516..80679 (+) | 1164 | WP_001142738.1 | phage major capsid protein | - |
| DXE62_RS00535 | - | 80748..81026 (+) | 279 | WP_000050973.1 | head-tail connector protein | - |
| DXE62_RS00540 | - | 81038..81370 (+) | 333 | WP_000395498.1 | hypothetical protein | - |
| DXE62_RS00545 | - | 81367..81768 (+) | 402 | WP_000110017.1 | hypothetical protein | - |
| DXE62_RS00550 | - | 81769..82164 (+) | 396 | WP_031863976.1 | DUF3168 domain-containing protein | - |
| DXE62_RS00555 | - | 82199..82840 (+) | 642 | WP_031865961.1 | major tail protein | - |
| DXE62_RS00560 | - | 82931..83386 (+) | 456 | WP_000169128.1 | Ig-like domain-containing protein | - |
| DXE62_RS00565 | gpG | 83444..83794 (+) | 351 | WP_000589165.1 | phage tail assembly chaperone G | - |
| DXE62_RS00570 | - | 83836..83994 (+) | 159 | WP_000438833.1 | hypothetical protein | - |
| DXE62_RS00575 | - | 84008..90208 (+) | 6201 | WP_114637614.1 | phage tail tape measure protein | - |
| DXE62_RS00580 | - | 90208..91032 (+) | 825 | WP_031918864.1 | phage tail family protein | - |
| DXE62_RS00585 | - | 91041..92624 (+) | 1584 | WP_000384474.1 | prophage endopeptidase tail family protein | - |
| DXE62_RS00590 | - | 92624..92914 (+) | 291 | WP_000179860.1 | hypothetical protein | - |
| DXE62_RS00595 | - | 92930..94840 (+) | 1911 | WP_000429551.1 | minor structural protein | - |
| DXE62_RS00600 | - | 94840..96306 (+) | 1467 | WP_000067142.1 | BppU family phage baseplate upper protein | - |
| DXE62_RS00605 | - | 96306..96695 (+) | 390 | WP_001166598.1 | DUF2977 domain-containing protein | - |
| DXE62_RS00610 | - | 96688..96852 (+) | 165 | WP_000916021.1 | XkdX family protein | - |
| DXE62_RS00615 | - | 96898..97197 (+) | 300 | WP_031861265.1 | DUF2951 family protein | - |
| DXE62_RS00620 | - | 97333..97635 (+) | 303 | WP_000339141.1 | phage holin | - |
| DXE62_RS00625 | - | 97647..99101 (+) | 1455 | WP_114637615.1 | N-acetylmuramoyl-L-alanine amidase | - |
| DXE62_RS00635 | - | 99839..100348 (+) | 510 | Protein_124 | Fic family protein | - |
| DXE62_RS00640 | sel26 | 100763..101515 (+) | 753 | WP_001807829.1 | staphylococcal enterotoxin type 26 | - |
| DXE62_RS00645 | - | 101718..101987 (-) | 270 | WP_000829750.1 | hypothetical protein | - |
| DXE62_RS00650 | mtnN | 102301..102987 (+) | 687 | WP_000579272.1 | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | - |
| DXE62_RS00655 | - | 103007..103534 (+) | 528 | WP_000524902.1 | YqeG family HAD IIIA-type phosphatase | - |
| DXE62_RS00660 | yqeH | 103535..104635 (+) | 1101 | WP_001280151.1 | ribosome biogenesis GTPase YqeH | - |
| DXE62_RS00665 | aroE | 104649..105455 (+) | 807 | WP_000666746.1 | shikimate dehydrogenase | - |
| DXE62_RS00670 | yhbY | 105459..105749 (+) | 291 | WP_000955234.1 | ribosome assembly RNA-binding protein YhbY | - |
| DXE62_RS00675 | nadD | 105752..106321 (+) | 570 | WP_000725164.1 | nicotinate (nicotinamide) nucleotide adenylyltransferase | - |
| DXE62_RS00680 | yqeK | 106311..106895 (+) | 585 | WP_001019324.1 | bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK | - |
| DXE62_RS00685 | rsfS | 106896..107249 (+) | 354 | WP_001088020.1 | ribosome silencing factor | - |
| DXE62_RS00690 | - | 107252..107968 (+) | 717 | WP_000084838.1 | class I SAM-dependent DNA methyltransferase | - |
| DXE62_RS00695 | comEA | 108008..108694 (+) | 687 | WP_001825349.1 | ComEA family DNA-binding protein | Machinery gene |
| DXE62_RS00700 | - | 108786..109247 (+) | 462 | WP_000439690.1 | ComE operon protein 2 | - |
| DXE62_RS00705 | comEC | 109252..111453 (+) | 2202 | WP_001807826.1 | DNA internalization-related competence protein ComEC/Rec2 | Machinery gene |
| DXE62_RS00710 | holA | 111510..112484 (+) | 975 | WP_001282570.1 | DNA polymerase III subunit delta | - |
Sequence
Protein
Download Length: 228 a.a. Molecular weight: 25783.41 Da Isoelectric Point: 9.3305
>NTDB_id=1149580 DXE62_RS00695 WP_001825349.1 108008..108694(+) (comEA) [Staphylococcus aureus isolate 6_LA_232]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTALKQSTSENSSLSKLEDVQVKDGDDSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTALKQSTSENSSLSKLEDVQVKDGDDSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT
Nucleotide
Download Length: 687 bp
>NTDB_id=1149580 DXE62_RS00695 WP_001825349.1 108008..108694(+) (comEA) [Staphylococcus aureus isolate 6_LA_232]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATGATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATGATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comEA | Staphylococcus aureus MW2 |
96.476 |
99.561 |
0.961 |
| comEA | Staphylococcus aureus N315 |
96.476 |
99.561 |
0.961 |