Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DXE56_RS10895 Genome accession   NZ_LT992464
Coordinates   2064065..2064634 (-) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus isolate 3_LA_115     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2059065..2069634
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE56_RS10850 - 2059539..2060147 (-) 609 WP_000020293.1 class I SAM-dependent methyltransferase -
  DXE56_RS10855 rplL 2060322..2060690 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DXE56_RS10860 rplJ 2060733..2061233 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  DXE56_RS10870 rplA 2061505..2062197 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  DXE56_RS10875 rplK 2062405..2062827 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  DXE56_RS10880 nusG 2063008..2063556 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DXE56_RS10885 secE 2063569..2063751 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DXE56_RS10890 rpmG 2063807..2063950 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  DXE56_RS10895 sigH 2064065..2064634 (-) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  DXE56_RS10900 - 2064716..2065240 (-) 525 WP_000664738.1 NYN domain-containing protein -
  DXE56_RS10905 rlmB 2065240..2065986 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DXE56_RS10910 - 2065994..2066398 (-) 405 WP_000370181.1 Mini-ribonuclease 3 -
  DXE56_RS10915 cysS 2066391..2067791 (-) 1401 WP_000631961.1 cysteine--tRNA ligase -
  DXE56_RS10920 cysE 2067775..2068422 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=1149570 DXE56_RS10895 WP_000872879.1 2064065..2064634(-) (sigH) [Staphylococcus aureus isolate 3_LA_115]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1149570 DXE56_RS10895 WP_000872879.1 2064065..2064634(-) (sigH) [Staphylococcus aureus isolate 3_LA_115]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment