Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   W903_RS05130 Genome accession   NZ_CP006910
Coordinates   981396..982709 (-) Length   437 a.a.
NCBI ID   WP_000042584.1    Uniprot ID   -
Organism   Streptococcus agalactiae CNCTC 10/84     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 976396..987709
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  W903_RS05110 (W903_1052) - 977875..978648 (-) 774 WP_000622397.1 DUF3307 domain-containing protein -
  W903_RS05115 (W903_1053) - 978645..979325 (-) 681 WP_000280307.1 SatD family protein -
  W903_RS05120 (W903_1054) ffh 979392..980957 (-) 1566 WP_000863593.1 signal recognition particle protein -
  W903_RS05125 (W903_1055) - 980975..981307 (-) 333 WP_000402075.1 putative DNA-binding protein -
  W903_RS05130 (W903_1056) ciaH 981396..982709 (-) 1314 WP_000042584.1 cell wall metabolism sensor histidine kinase WalK Regulator
  W903_RS05135 (W903_1057) ciaR 982693..983373 (-) 681 WP_000590620.1 response regulator transcription factor Regulator
  W903_RS05140 (W903_1058) - 983535..986084 (-) 2550 WP_000859374.1 M1 family metallopeptidase -
  W903_RS05145 (W903_1059) phoU 986230..986883 (-) 654 WP_000946330.1 phosphate signaling complex protein PhoU -
  W903_RS05150 (W903_1060) pstB 986917..987675 (-) 759 WP_000193363.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 49678.12 Da        Isoelectric Point: 9.4961

>NTDB_id=114953 W903_RS05130 WP_000042584.1 981396..982709(-) (ciaH) [Streptococcus agalactiae CNCTC 10/84]
MSKPIKISKFKKNVSDSHFIHFFTVFSGIFLVMTVIILQVMRYGVYSSVDSSLKYISTHPKNYINMVMSRTAAYLDNSNI
ASVKLKPGGQTVANTDILLFTSEEEVINYFDAFSNYQFLKPNKKNLGGISELTLTNIFGQDETYHAVTVKVNNPAYPNVT
YMTAIVNIDQLVNAKERYEKIIIFVMTTFWIISIGASIYLAKWAQKPIIENYERQKAFVENASHELRTPLAVLQNRLETL
FRKPNATILENSENIASSLDEVRNMRILTTNLLNLARRDDGIKPELAVIKPTLFDSIFENYDLIAQENGKNFTGHNMIQD
SFKTDKTLLKQLMTILFDNAIKYTDNDGSIDFTISETDKYLFLEIADNGPGISEEDKVRIFDRFYRVDKARTRQQGGFGL
GLSLAQQIVNSLRGNITVIDNKPRGSIFKIKLPKVKG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=114953 W903_RS05130 WP_000042584.1 981396..982709(-) (ciaH) [Streptococcus agalactiae CNCTC 10/84]
ATGTCGAAACCGATTAAGATAAGTAAATTCAAAAAAAATGTCTCAGATAGTCATTTTATCCATTTTTTCACAGTTTTTAG
TGGTATTTTTCTGGTTATGACTGTTATCATCCTCCAAGTCATGCGCTATGGTGTTTATTCTTCTGTTGATAGTAGTTTAA
AGTATATCAGTACCCATCCTAAAAATTACATCAATATGGTTATGTCACGTACTGCTGCCTACCTAGATAACTCCAATATC
GCAAGTGTCAAGTTAAAACCCGGCGGTCAGACAGTAGCTAATACTGATATTCTTCTTTTTACATCAGAAGAAGAAGTCAT
TAACTATTTTGACGCATTTTCAAACTATCAGTTTTTAAAACCTAATAAAAAAAATCTAGGTGGCATTAGTGAATTAACTT
TAACCAACATCTTTGGTCAAGATGAGACATATCATGCTGTCACCGTAAAAGTTAATAACCCTGCTTATCCTAATGTGACT
TACATGACAGCTATTGTTAATATTGATCAATTAGTAAATGCTAAAGAACGCTATGAAAAAATTATTATATTTGTCATGAC
TACTTTTTGGATTATTTCAATTGGAGCAAGTATCTACTTAGCTAAATGGGCACAAAAACCGATTATAGAAAACTACGAAA
GACAGAAGGCTTTTGTCGAAAATGCTAGCCACGAGCTGCGTACTCCTCTAGCTGTCTTACAAAATCGCCTAGAAACGCTA
TTCAGAAAACCGAATGCCACCATTTTAGAAAATAGTGAAAATATCGCTTCAAGTCTAGATGAAGTACGAAATATGCGTAT
TTTAACCACTAATCTTTTAAACTTAGCAAGGCGTGATGATGGAATCAAACCAGAATTAGCTGTTATTAAGCCTACACTTT
TTGATAGTATCTTTGAGAATTATGATCTAATCGCCCAAGAGAATGGTAAAAATTTTACTGGACATAATATGATCCAAGAT
AGTTTCAAAACAGATAAGACACTGCTAAAACAACTCATGACTATTTTATTTGATAATGCTATAAAATATACTGACAATGA
TGGTAGCATTGACTTTACCATATCTGAAACTGATAAGTATCTCTTTTTAGAAATCGCTGATAATGGACCAGGAATTTCAG
AGGAGGATAAAGTCAGAATTTTTGATCGTTTTTACCGTGTTGACAAAGCAAGAACACGACAACAAGGAGGGTTTGGCCTC
GGCCTTTCTTTAGCTCAACAAATCGTTAACTCACTGCGAGGTAATATTACAGTAATTGATAATAAACCTAGAGGCAGTAT
TTTTAAGATAAAACTACCAAAAGTAAAAGGTTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(216-281)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

60.14

98.169

0.59
  ciaH Streptococcus pneumoniae Rx1

51.905

96.11

0.499
  ciaH Streptococcus pneumoniae D39

51.905

96.11

0.499
  ciaH Streptococcus pneumoniae R6

51.905

96.11

0.499
  ciaH Streptococcus pneumoniae TIGR4

51.905

96.11

0.499

Multiple sequence alignment