Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DXE29_RS04025 Genome accession   NZ_LT992463
Coordinates   806616..807185 (+) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus isolate 2_LA_86     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 801616..812185
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE29_RS04000 cysE 802828..803475 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  DXE29_RS04005 cysS 803459..804859 (+) 1401 WP_000631961.1 cysteine--tRNA ligase -
  DXE29_RS04010 - 804852..805256 (+) 405 WP_000370181.1 Mini-ribonuclease 3 -
  DXE29_RS04015 rlmB 805264..806010 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DXE29_RS04020 - 806010..806534 (+) 525 WP_000664738.1 NYN domain-containing protein -
  DXE29_RS04025 sigH 806616..807185 (+) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  DXE29_RS04030 rpmG 807300..807443 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  DXE29_RS04035 secE 807499..807681 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DXE29_RS04040 nusG 807694..808242 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DXE29_RS04045 rplK 808423..808845 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  DXE29_RS04050 rplA 809053..809745 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  DXE29_RS04060 rplJ 810017..810517 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  DXE29_RS04065 rplL 810560..810928 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DXE29_RS04070 - 811103..811711 (+) 609 WP_000020293.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=1149496 DXE29_RS04025 WP_000872879.1 806616..807185(+) (sigH) [Staphylococcus aureus isolate 2_LA_86]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1149496 DXE29_RS04025 WP_000872879.1 806616..807185(+) (sigH) [Staphylococcus aureus isolate 2_LA_86]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment