Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DXE65_RS05565 Genome accession   NZ_LT992462
Coordinates   1073222..1073791 (-) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus isolate 5_3949     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1068222..1078791
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE65_RS05520 - 1068696..1069304 (-) 609 WP_000020293.1 class I SAM-dependent methyltransferase -
  DXE65_RS05525 rplL 1069479..1069847 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DXE65_RS05530 rplJ 1069890..1070390 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  DXE65_RS05540 rplA 1070662..1071354 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  DXE65_RS05545 rplK 1071562..1071984 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  DXE65_RS05550 nusG 1072165..1072713 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DXE65_RS05555 secE 1072726..1072908 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DXE65_RS05560 rpmG 1072964..1073107 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  DXE65_RS05565 sigH 1073222..1073791 (-) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  DXE65_RS05570 - 1073873..1074397 (-) 525 WP_000664738.1 NYN domain-containing protein -
  DXE65_RS05575 rlmB 1074397..1075143 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DXE65_RS05580 - 1075151..1075555 (-) 405 WP_000370181.1 Mini-ribonuclease 3 -
  DXE65_RS05585 cysS 1075548..1076948 (-) 1401 WP_000631961.1 cysteine--tRNA ligase -
  DXE65_RS05590 cysE 1076932..1077579 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=1149458 DXE65_RS05565 WP_000872879.1 1073222..1073791(-) (sigH) [Staphylococcus aureus isolate 5_3949]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1149458 DXE65_RS05565 WP_000872879.1 1073222..1073791(-) (sigH) [Staphylococcus aureus isolate 5_3949]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment