Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DXE60_RS08390 Genome accession   NZ_LT992461
Coordinates   1572665..1573234 (+) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus isolate 8_LA_272     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1567665..1578234
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE60_RS08365 cysE 1568877..1569524 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  DXE60_RS08370 cysS 1569508..1570908 (+) 1401 WP_000631961.1 cysteine--tRNA ligase -
  DXE60_RS08375 - 1570901..1571305 (+) 405 WP_000370181.1 Mini-ribonuclease 3 -
  DXE60_RS08380 rlmB 1571313..1572059 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DXE60_RS08385 - 1572059..1572583 (+) 525 WP_000664738.1 NYN domain-containing protein -
  DXE60_RS08390 sigH 1572665..1573234 (+) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  DXE60_RS08395 rpmG 1573349..1573492 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  DXE60_RS08400 secE 1573548..1573730 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DXE60_RS08405 nusG 1573743..1574291 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DXE60_RS08410 rplK 1574472..1574894 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  DXE60_RS08415 rplA 1575102..1575794 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  DXE60_RS08425 rplJ 1576066..1576566 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  DXE60_RS08430 rplL 1576609..1576977 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DXE60_RS08435 - 1577152..1577760 (+) 609 WP_000020293.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=1149413 DXE60_RS08390 WP_000872879.1 1572665..1573234(+) (sigH) [Staphylococcus aureus isolate 8_LA_272]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1149413 DXE60_RS08390 WP_000872879.1 1572665..1573234(+) (sigH) [Staphylococcus aureus isolate 8_LA_272]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment