Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DXE39_RS01890 Genome accession   NZ_LT992460
Coordinates   349592..350161 (-) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus isolate 9_LA_281     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 344592..355161
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE39_RS01845 - 345066..345674 (-) 609 WP_000020293.1 class I SAM-dependent methyltransferase -
  DXE39_RS01850 rplL 345849..346217 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DXE39_RS01855 rplJ 346260..346760 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  DXE39_RS01865 rplA 347032..347724 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  DXE39_RS01870 rplK 347932..348354 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  DXE39_RS01875 nusG 348535..349083 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DXE39_RS01880 secE 349096..349278 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DXE39_RS01885 rpmG 349334..349477 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  DXE39_RS01890 sigH 349592..350161 (-) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  DXE39_RS01895 - 350243..350767 (-) 525 WP_000664738.1 NYN domain-containing protein -
  DXE39_RS01900 rlmB 350767..351513 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DXE39_RS01905 - 351521..351925 (-) 405 WP_000370181.1 Mini-ribonuclease 3 -
  DXE39_RS01910 cysS 351918..353318 (-) 1401 WP_000631961.1 cysteine--tRNA ligase -
  DXE39_RS01915 cysE 353302..353949 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=1149358 DXE39_RS01890 WP_000872879.1 349592..350161(-) (sigH) [Staphylococcus aureus isolate 9_LA_281]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1149358 DXE39_RS01890 WP_000872879.1 349592..350161(-) (sigH) [Staphylococcus aureus isolate 9_LA_281]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment