Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DXE63_RS14715 Genome accession   NZ_LT992458
Coordinates   2847088..2847657 (-) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus isolate 7_4623     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2842088..2852657
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE63_RS14670 - 2842562..2843170 (-) 609 WP_000020293.1 class I SAM-dependent methyltransferase -
  DXE63_RS14675 rplL 2843345..2843713 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DXE63_RS14680 rplJ 2843756..2844256 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  DXE63_RS14690 rplA 2844528..2845220 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  DXE63_RS14695 rplK 2845428..2845850 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  DXE63_RS14700 nusG 2846031..2846579 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DXE63_RS14705 secE 2846592..2846774 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DXE63_RS14710 rpmG 2846830..2846973 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  DXE63_RS14715 sigH 2847088..2847657 (-) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  DXE63_RS14720 - 2847739..2848263 (-) 525 WP_000664738.1 NYN domain-containing protein -
  DXE63_RS14725 rlmB 2848263..2849009 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DXE63_RS14730 - 2849017..2849421 (-) 405 WP_000370181.1 Mini-ribonuclease 3 -
  DXE63_RS14735 cysS 2849414..2850814 (-) 1401 WP_000631961.1 cysteine--tRNA ligase -
  DXE63_RS14740 cysE 2850798..2851445 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=1149352 DXE63_RS14715 WP_000872879.1 2847088..2847657(-) (sigH) [Staphylococcus aureus isolate 7_4623]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1149352 DXE63_RS14715 WP_000872879.1 2847088..2847657(-) (sigH) [Staphylococcus aureus isolate 7_4623]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment